myocardial injury in infants ventilated on the paediatric intensive care unit a case control study心肌损伤婴儿在儿科重症监护病房通风一个病例对照研究.pdfVIP
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myocardial injury in infants ventilated on the paediatric intensive care unit a case control study心肌损伤婴儿在儿科重症监护病房通风一个病例对照研究
Available online /content/10/5/R128
Vol 10 No 5 Open Access
Research
Myocardial injury in infants ventilated on the paediatric intensive
care unit: a case control study
Simon J Clark, Michael Eisenhut, Dorothea Sidaras, Stephen W Hancock, Paul Newland and
Kent Thorburn
Royal Liverpool Childrens NHS Trust, Eaton Road, Liverpool L12 2AP, UK
Corresponding author: Michael Eisenhut, michael_eisenhut@
Received: 11 Jul 2006 Revisions requested: 16 Aug 2006 Revisions received: 18 Aug 2006 Accepted: 11 Sep 2006 Published: 11 Sep 2006
Critical Care 2006, 10:R128 (doi:10.1186/cc5040)
This article is online at: /content/10/5/R128
© 2006 Clark et al.; licensee BioMed Central Ltd.
This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction Cardiac troponin T (cTnT) has been used to (interquartile range (IQR)) age of 20 (12 to 34) weeks,
assess prevalence of myocardial injury in critically ill children. significantly older than cases, with a median age of 6.5 (0.3 to
The majority of studies investigated patients undergoing cardiac 20.6) weeks. CTnT levels were, with a median (IQR) of 18 (10
surgery. Myocardial injury has been associated with increased to 60) pg/ml, significantly higher in admissions to the PICU than
mortality. Our objectives were to investigate whether cTnT levels in controls, with a median level of 10 (10 to 10) pg/ml (95th
are elevated in infants without congenital heart disease admitted centile of 20
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