negative-pressure cavitation extraction of four main vinca alkaloids from catharanthus roseus leaves负压空化四个主要的提取长春花生物碱从catharanthus roseus也叫叶子.pdfVIP

下载本文档

1
0
约4.85万字
约 11页
2017-09-11 发布于上海
举报
版权申诉

negative-pressure cavitation extraction of four main vinca alkaloids from catharanthus roseus leaves负压空化四个主要的提取长春花生物碱从catharanthus roseus也叫叶子.pdf

1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击这里二次下载。
3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
7、VIP文档为合作方或网友上传，每下载1次，网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档

negative-pressure cavitation extraction of four main vinca alkaloids from catharanthus roseus leaves负压空化四个主要的提取长春花生物碱从catharanthus roseus也叫叶子

Molecules 2012, 17, 8742-8752; doi:10.3390/molecule OPEN ACCESS molecules ISSN 1420-3049 /journal/molecules Article Negative-Pressure Cavitation Extraction of Four Main Vinca Alkaloids from Catharanthus roseus Leaves Fansong Mu 1,2,3,†, Liuqing Yang 1,2,3,†, Wei Wang 1,2,3, Meng Luo 1,2,3,4,*, Yujie Fu 1,2,3, Xiaorui Guo 1,2,3 and Yuangang Zu 1,2,3,* 1 Engineering Research Center of Forestry Bio-preparation, Ministry of Education, Northeast Forestry University, Harbin 150040, China 2 Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China 3 State Engineering Laboratory of Bio-Resource Eco-Utilization, Harbin 150040, China 4 Zhejiang Hisun Pharmaceutical Co. Ltd., Taizhou 318000, China † These authors contributed equally to this work. * Authors to whom correspondence should be addressed; E-Mails: wslm_5555@ (M.L.); zygorl@ (Y.Z.); Tel.: +86-451-8219- 1517 (M.L.); Fax: +86-451-8219-2082 (M.L.). Received: 15 May 2012; in revised form: 11 July 2012 / Accepted: 13 July 2012 / Published: 25 July 2012 Abstract: In the present study, an improved method termed negative-pressure cavitation extraction (NPCE) followed by reverse phase high-performance liquid chromatography (RP-HPLC) was developed for the extraction and quantification of vindoline (VDL), catharanthine (CTR), vincristine (VCR) and vinblastine (VLB) from Catharanthus roseus leaves. The optimized method employed 60-mesh particles, 80% ethanol, a negative pr