phytalgic?, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip a randomised double-blind placebo-controlled clinical trialphytalgic ,一个食品补充剂,与安慰剂患者膝关节或髋关节骨关节炎的随机双盲安慰剂对照的临床试验.pdfVIP
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phytalgic?, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip a randomised double-blind placebo-controlled clinical trialphytalgic ,一个食品补充剂,与安慰剂患者膝关节或髋关节骨关节炎的随机双盲安慰剂对照的临床试验
Available online /content/11/6/R192
Vol 11 No 6 Open Access
Research article
Phytalgic®, a food supplement, vs placebo in patients with
osteoarthritis of the knee or hip: a randomised double-blind
placebo-controlled clinical trial
1 1,2,3 1,2,3 1 4
Alain Jacquet , Pierre-Olivier Girodet , Antoine Pariente , Karelle Forest , Laurent Mallet and
Nicholas Moore1,2,3
1Department of Pharmacology, University of Bordeaux, 146 rue Léo Saignat, 33076, Bordeaux, France
2CHU de Bordeaux, 12 rue Dabernat, 33404 Talence, France
3Centre dInvestigation Clinique, INSERM CIC0005, 146 rue Léo Saignat, 33076, Bordeaux, France
4Phythea, 13 Rue Elsa Triolet, 77176 Savigny, France
Corresponding author: Nicholas Moore, nicholas.moore@pharmaco.u-bordeaux2.fr
Received: 8 Jul 2009 Revisions requested: 9 Sep 2009 Revisions received: 27 Nov 2009 Accepted: 16 Dec 2009 Published: 16 Dec 2009
Arthritis Research Therapy 2009, 11:R192 (doi:10.1186/ar2891)
This article is online at: /content/11/6/R192
© 2009 Jacquet et al.; licensee BioMed Central Ltd.
This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Introduction The medicinal treatment of osteoarthritis (OA) is Results After three months of treatment, the mean use of
mostly symptomatic to relieve pain and incapacity with analgesics in the active arm (6.5 PET/week) vs. the placebo arm
analgesics and non-steroidal anti-inflammatory drugs (NSAIDs), (1
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