原创力文档the choice of the intravenous fluid influences the tolerance of acute normovolemic anemia in anesthetized domestic pigs静脉液体的选择影响急性normovolemic贫血的公差在国内猪麻醉.pdfVIP
- 1、原创力文档（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。。
- 2、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 3、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
- 4、该文档为VIP文档，如果想要下载，成为VIP会员后，下载免费。
- 5、成为VIP后，下载本文档将扣除1次下载权益。下载后，不支持退款、换文档。如有疑问请联系我们。
- 6、成为VIP后，您将拥有八大权益，权益包括：VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 7、VIP文档为合作方或网友上传，每下载1次， 网站将根据用户上传文档的质量评分、类型等，对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
the choice of the intravenous fluid influences the tolerance of acute normovolemic anemia in anesthetized domestic pigs静脉液体的选择影响急性normovolemic贫血的公差在国内猪麻醉
Pape et al. Critical Care 2012, 16:R69
/content/16/2/R69
RESEARCH Open Access
The choice of the intravenous fluid influences the
tolerance of acute normovolemic anemia in
anesthetized domestic pigs
1* 1 1 1 1 1 2
Andreas Pape , Saskia Kutschker , Harry Kertscho , Peter Stein , Oliver Horn , Mischa Lossen , Bernhard Zwissler
and Oliver Habler3
Abstract
Introduction: The correction of hypovolemia with acellular fluids results in acute normovolemic anemia. Whether
the choice of the infusion fluid has an impact on the maintenance of oxygen (O2) supply during acute
normovolemic anemia has not been investigated so far.
Methods: Thirty-six anesthetized and mechanically ventilated pigs were hemodiluted to their physiological limit of
anemia tolerance, reflected by the individual critical hemoglobin concentration (Hbcrit). Hbcrit was defined as the
Hb-concentration corresponding with the onset of supply-dependency of total body O -consumption (VO ). The
2 2
hemodilution protocol was randomly performed with either tetrastarch (6% HES 130/0.4, TS-group, n = 9), gelatin
(3.5% urea-crosslinked polygeline, GEL-group, n = 9), hetastarch (6% HES 450/0.7, HS-group, n = 9) or Ringer’s
solution (RS-group, n = 9). The primary endpoint was the dimension of Hbcrit, secondary endpoints were
parameters of central hemodynamics, O2 transport and tissue oxygenation.
Results: In each animal, normovolemia was maintained throughout the protocol. Hbcrit was met at 3.7 ± 0.6 g/dl
(RS), 3.0 ± 0.6 g/dl (HS P 0.05 vs. RS), 2.7 ± 0.6 g/dl (GEL, P 0.05 vs. RS) and 2.1 ± 0.4 g/dl (T
您可能关注的文档
- the abilities of improved schizophrenia patients to work and live independently in the community a 10-year long-term outcome study from mumbai, india改善精神分裂症患者的能力独立工作和生活在社区10年期的长期研究结果从孟买,印度.pdf
- the ability of a nanofiltration membrane to remove hardness and ions from diluted seawater纳滤膜去除硬度的能力和离子稀释海水.pdf
- the absence of cd47 promotes nerve fiber growth from cultured ventral mesencephalic dopamine neurons没有cd47促进神经纤维生长培养腹侧中脑多巴胺神经元.pdf
- the abundance of pink-pigmented facultative methylotrophs in the root zone of plant species in invaded coastal sage scrub habitat丰富的pink-pigmented兼性methylotrophs在入侵植物的根区沿海圣人擦洗的栖息地.pdf
- the 2011 brisbane floods causes, impacts and implications2011年布里斯班洪水的原因,影响和意义.pdf
- the academic medical center linear disability score for evaluation of physical reserve on admission to the icu can we query the relatives学术医学中心线性残疾分数评价物理储备进入icu我们可以查询的亲戚.pdf
- the aca training programme to improve communication between general practitioners and their palliative care patients development and applicabilityaca培训计划来提高全科医生和姑息治疗患者之间的通信发展和适用性.pdf
- the 9-phenyl-9-fluorenyl group for nitrogen protection in enantiospecific synthesis9-phenyl-9-fluorenyl组enantiospecific合成的氮保护.pdf
- the aaa-atpase vps4 regulates extracellular secretion and lysosomal targeting of α-synuclein的aaa-atpase vps4α-synuclein调节胞外分泌物和溶酶体的目标.pdf
- the acceptability of internet-based treatment and characteristics of an adult sample with obsessive compulsive disorder an internet survey基于互联网的可接受性治疗和一个成年人样本的特征与强迫症网上调查.pdf
- the chromatin remodeling factor smarcb1 forms a complex with human cytomegalovirus proteins ul114 and ul44染色质重塑因子smarcb1形成一个复杂的人类巨细胞病毒蛋白质ul114和ul44.pdf
- the chitinolytic activities of streptomyces sp. th-11链霉菌属的chitinolytic活动th-11 sp.pdf
- the ciliate paramecium shows higher motility in non-uniform chemical landscapes纤毛虫草履虫显示高运动性非均匀化学景观.pdf
- the cinnamon-derived dietary factor cinnamic aldehyde activates the nrf2-dependent antioxidant response in human epithelial colon cells肉桂醛的cinnamon-derived膳食因素激活nrf2-dependent人类结肠上皮细胞抗氧化反应.pdf
- the chromosomal passenger complex activates polo kinase at centromeres在着丝粒染色体乘客复杂激活马球激酶.pdf
- the chromatin remodelling complex b-wich changes the chromatin structure and recruits histone acetyl-transferases to active rrna genes染色质重塑复合物b-wich改变染色质结构和招聘组蛋白acetyl-transferases主动核糖体rna基因.pdf
- the chronic protective effects of limb remote preconditioning and the underlying mechanisms involved in inflammatory factors in rat stroke慢性肢体远程预处理的保护作用和潜在机制参与炎性因子在大鼠中风.pdf
- the chromosome 9p21.3 coronary heart disease risk allele is associated with altered gene expression in normal heart and vascular tissues染色体9 . 3冠心病风险等位基因与正常心脏和血管组织中基因表达改变.pdf
- the chromatin remodelling factor datrx is involved in heterochromatin formation染色质重塑因子datrx参与异染色质的形成.pdf
- the circadian clock regulates auxin signaling and responses in arabidopsis生物钟调节生长素信号在拟南芥和响应.pdf
文档评论（0）