what happens in between human oscillatory brain activity related to crossmodal spatial cueing发生在人类的振荡之间大脑活动相关交叉空间提示.pdfVIP

What Happens in Between? Human Oscillatory Brain Activity Related to Crossmodal Spatial Cueing 1 2 2 ¨ 1 ¨ 1 1 3 Maja U. Trenner *, Hauke R. Heekeren , Markus Bauer , Konstanze Rossner , Rudiger Wenzel , Arno Villringer , Manfred Fahle ´ ¨ 1 Berlin NeuroImaging Center, Neurologische Klinik und Poliklinik, Charite Universitatsmedizin Berlin, Berlin, Germany, 2 Max Planck Institute for Human Development, Berlin, Germany, 3 Centre for Cognitive Science, Human Neurobiology, University of Bremen, Bremen, Germany Previous studies investigated the effects of crossmodal spatial attention by comparing the responses to validly versus invalidly cued target stimuli. Dynamics of cortical rhythms in the time interval between cue and target might contribute to cue effects on performance. Here, we studied the influence of spatial attention on ongoing oscillatory brain activity in the interval between cue and target onset. In a first experiment, subjects underwent periods of tactile stimulation (cue) followed by visual stimulation (target) in a spatial cueing task as well as tactile stimulation as a control. In a second experiment, cue validity was modified to be 50%, 75%, or else 25%, to separate effects of exogenous shifts of attention caused by tactile stimuli from that of endogenous shifts. Tactile stimuli produced: 1) a stronger lateralization of the sensorimotor beta-rhythm rebound (15–22 Hz) after tactile stimuli serving as cues versus not serving as cues; 2) a suppression of the occipital alpha-rhythm (7–13 Hz) appearing only in the cueing task (this suppression was stronger contralateral to the endogenously attended side and was predictive of behavioral success); 3) an increa