the risk of obesity by assessing infant growth against the uk-who charts compared to the uk90 reference findings from the born in bradford birth cohort study肥胖的风险评估婴儿对英国增长图表相比uk90参考发现出生在布拉德福德出生队列研究.pdfVIP

the risk of obesity by assessing infant growth against the uk-who charts compared to the uk90 reference findings from the born in bradford birth cohort study肥胖的风险评估婴儿对英国增长图表相比uk90参考发现出生在布拉德福德出生队列研究.pdf

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the risk of obesity by assessing infant growth against the uk-who charts compared to the uk90 reference findings from the born in bradford birth cohort study肥胖的风险评估婴儿对英国增长图表相比uk90参考发现出生在布拉德福德出生队列研究

Johnson et al. BMC Pediatrics 2012, 12:104 /1471-2431/12/104 RESEARCH ARTICLE Open Access The risk of obesity by assessing infant growth against the UK-WHO charts compared to the UK90 reference: findings from the Born in Bradford birth cohort study William Johnson1*, John Wright2 and Noël Cameron3 Abstract Background: The new growth charts in the UK, the UK-WHO charts, comprise prescriptive data from the WHO standard between two weeks and four years of age. Little is known about the development of obesity risk in normal UK infants, who are necessarily not fed according to the WHO recommendations and do not live in constraint-free environments (the selection criteria of the WHO standard source sample), using the new charts. Here, we investigated infant growth trajectories and traits indicative of childhood obesity using the UK-WHO charts, with the aim to clearly document the implications of adopting the new charts on UK growth monitoring practice. Methods: Mixed effects models were applied to serial weight and length data from 2181 infants (1187 White; 994 Pakistani) in the Born in Bradford birth cohort study to produce curves from 10 days to 15 months of age. Individual monthly estimates were converted to Z-scores and were plotted by sex and ethnic group. The relative risks (RR) of traits indicative of childhood obesity, including high BMI and rapid weight gain, using the UK-WHO charts compared to the previously used UK90 reference were calculated for all infants together and for White and Pakistani infants separately. Results: Both ethnic groups demonstrated patterns of growth similar to the UK-WHO charts in length but not in weight. The resulting pattern for BMI was remarkable, with an average gain of 1.0 Z-score between two and 12 months of age. The UK-WHO charts were significantly (p 0.05) more likely t

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