异甘草酸镁与硫普罗宁在乳腺癌化疗中预防肝损伤作用的比较_宋玮.pdfVIP

2011 15 9 Jour al of Cli ical Medici e i Practice 73 宋 玮 ( , , 223300) : 118 , ( 40 ) ( 40 ) ( 38 ) 4 d 1 0 , 2. 5% ; 5 , 12. 5% ; 11 , 28. 94% : ; ; ; ; : R 7379 : A : 1672- 2353( 2011) 09- 0073- 03 Effect of Magnesium Isoglycyrrhizinate and Tiopronin on preventing hepatic injury induced by chemotherapy in breast cancer SONG Wei ( H uaian P eop les N o. 1 H osp ital Af f iliated to N anj ing M ed ical Un iv ersity , H ua ian, Jiang su, 223300) BSTR CT: Objective To compare Mag esium Isoglycyrrhiz ate a d T iopro i s effect o preve ti g hepatic i jury i duced by chemotherapy i the treatme t of breast ca cer. Methods 118 patie ts for breast ca cer chemotherapy w ere divided ra domly i to three groups: M ag esium Iso- glycyrrhiz ate treatme t group ( n = 40) , Tiopro i treatme t group ( n = 40) a d co trol group ( n = 38) . T he data w ere a alyzed after all the chemotherapy w as give . Results T he results showed that 1 ( 2. 5% ) case had hepatic fu ctio ab ormality i Mag esium Isoglycyrrhiz ate treatme t group, 5 cases ( 12. 5%) w ith hepatic fu ctio ab ormality i Tiopro i treatme t group, 11 cases w ith hepatic fu ctio ab ormality i bla k co trol group, 28. 94% . Conclusion M ag esium Isoglycyrrhiz ate ca be w idely used i LC. KEY WORDS: breast ca cer; chemotherapy ; hepatic i jury; Mag esium Isoglycyrrhiz ate; T iopro i 20 70 , 1 , 2% [ 1] 120 1. 1 一般资料 [ 2] , 118 , , [ 3] , , ,