影响鼻腔鼻窦内翻性乳头状瘤复发的相关因素分析.docVIP

影响鼻腔鼻窦内翻性乳头状瘤复发的相关因素分析 王茂华 关兵 于爱民 戴炳译 严齐 陈思思 中南大学湘雅二医院耳鼻咽喉头颈外科 江苏省苏北人民医院耳鼻咽喉头颈外科 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的:探讨影响鼻腔鼻窦内翻性乳头状瘤 (SNIP) 复发的危险因素及减少复发的方法。方法:回顾性分析34例SNIP患者的临床资料。均为单侧发病, 按Krouse分级方法进行临床分级。均在鼻内镜下手术治疗, 其中单纯鼻内镜下肿瘤切除术20例, 鼻内镜下联合泪前隐窝入路手术14例。术后随访1236个月, 统计患者复发情况并分析复发的影响因素。结果:34例SNIP患者术后总复发率为17.65% (6/34) ;单纯鼻内镜下肿瘤切除术复发率25.00% (5/20) , 鼻内镜下联合泪前隐窝入路手术复发率7.14% (1/14) , 两者比较差异无统计学意义 (χ2=1.807, P0.05) 。Ⅰ、Ⅱ、Ⅲ、Ⅳ级复发率分别为0 (0/4) 、15.0% (3/20) 、33.3% (3/9) 和0 (0/1) , 不同分级患者比较, 差异无统计学意义 (χ2=2.692, P0.05) 。结论:单纯鼻内镜下肿瘤切除术和鼻内镜下联合泪前隐窝入路手术均为治疗SNIP的有效方法。鼻部手术史及肿瘤生发中心是影响患者复发的危险因素。术前进行详细检查、术中彻底切除肿瘤、术后定期内镜检查是减少复发的关键。 关键词： 鼻腔鼻窦内翻性乳头状瘤; 内镜外科手术; 复发; 预后; 作者简介：关兵, E-mail:aliceguan0685@ 收稿日期：2017-09-06 Analysis of the recurrence related factors of sinonasal inverted papilloma WANG Maohua GUAN Bing YU Aimin DAI Bingyi YAN Qi CHEN Sisi Department of Otorhinolaryngology Head and Neck Surgery, Xiangya No.2Hospital of Central South University; Department of Otorhinolaryngology Head and Neck Surgery, Jiangsu Subei Peoples Hospital; Abstract： Objective:To evaluate the influence risk factors of recurrence and the methods for reducing recurrence of sinonasal inverted papilloma (SNIP) .Method:Clinical data of 34 patients with SNIP were analyzed retrospectively.All of them were unilateral onset.The diagnosis was confirmed pathologically and the range of lesions was determined by endoscopic and imaging examination;clinical classification according to Krouse classification method;All operations were performed under nasal endoscope, of which 20 cases were operated by simple nasal endoscope, and 14 cases were operated by endoscopic anterior lacrimal recess approach.The patients were followed up for 12-36 months.The curative effects were observed and the prognostic factors of the patients were analyzed.Result:Thirty-four cases of SNIP patients with postoperative recurrence rate was 17.65% (6/34) ;simple nasal endoscopic surgery in 20 cases,