手术治疗与药物保守治疗甲状腺功能亢进55例临床疗效对比观察.docVIP

精品论文 参考文献 手术治疗与药物保守治疗甲状腺功能亢进55例临床疗效对比观察 胡泉 孙圣荣 　　(武汉大学人民医院甲乳外科 437100) 　　【摘要】目的：通过研究比较手术治疗与药物保守治疗对于甲状腺功能亢进患者的临床效果对比情况。方法：将我院2011年1月至2013年12月接收并进行治疗的甲状腺功能亢进患者中，随机选择手术治疗26例与药物保守治疗29例患者，进行回顾性分析和研究，并将抽取的研究对象分为观察组(手术治疗)和对照组(药物保守治疗)两组，对比分析两组患者的治疗效果和特点。对收集的数据资料运用SPSS 20.0进行分析,计量资料采用配对t检验、计数资料采用卡方检验进行分析。结果：甲状腺功能亢进患者55名，其中男性9例、女性46例，年龄分布在16-62岁之间，平均年龄为32.94plusmn;8.14岁，两组患者年龄、性别、肿瘤特诊、并发症等一般人口学特征无统计学差异(Pgt;0.05)；在两组患者治疗效果、治疗后并发症以及不良反应上经检验均Plt;0.05，仍然存在统计学上差异；并且在SF-36生存质量评分上，也有统计学差异。但是在治疗后复发情况上没有差异。结论：对于甲状腺功能亢进患者，经过甲状腺大部分切除手术治疗相比于药物保守治疗在治疗效果上相对较好，为日后治疗甲状腺功能亢进的治疗方案选择提供了思路。 　　【关键词】手术治疗 药物保守治疗 甲状腺功能亢进 临床疗效对比 　　【中图分类号】R581.1 【文献标识码】A 【文章编号】2095-1752（2014）15-0119-02 　　55 cases of Compared clinical efficacy Between Surgical treatment and medicine conservative treatment in hyperthyroidism 　　【Abstract】 Objective: To compare the clinical effect of hyperthyroidism between surgical treatment and medicine conservative treatment. Methods: Selected cases randomly with 26 patients of operative treatment as well as 29 patients with medicine conservative treatment by using retrospective analysis and research from January 2011 to December 2013 , these cases were divided into observation group (surgery) and control group (medicine conservative treatment) , compare and analyse the curative effects and characteristics of two groups. Using SPSS 20.0 analyze the collected data, measurement data was analysed by paired t test and counting data was analysed by chi-square analysis.Results: There were 55 cases with hyperthyroidism with 9 cases of males and cases of females respectively , the average age was 32.94plusmn;8.14 years old with age distribution was from 16 to 62,there is no statistical difference in general demographic characteristics like age, gender, tumor diagnosis, complications(P gt; 0.05); there is still a statistical difference in treatment effects, complications after treatment and adverse reactions (P lt; 0.05); in addit