目标导向液体在ASAⅡ～Ⅲ级胶质瘤手术治疗中的应用价值.docVIP

目标导向液体在ASAⅡ～Ⅲ级胶质瘤手术治疗中的应用价值 徐辉 解放军第四二五医院 X 关注成功！ 加关注后您将方便地在 我的关注中得到本文献的被引频次变化的通知！ 新浪微博 腾讯微博 人人网 开心网 豆瓣网 网易微博 摘????要： 目的探讨目标导向液体治疗应用于ASAⅡⅢ级胶质瘤患者手术切除中对其术中血流动力学及脑氧饱和度的影响, 为患者安全手术提供保障。方法回顾性分析86例ASAⅡⅢ级胶质瘤患者的临床手术情况, 其中实施常规治疗者为对照组 (43例) , 以目标导向液体治疗者为观察组 (43例) , 记录两组患者手术前30 min (T0) 、麻醉诱导后15 min (T1) 、手术中60 min (T2) 、手术中120 min (T3) 、手术中180 min (T4) 及手术完成时 (T5) 时血流动力学各项指标、心指数 (CI) 及脑氧饱和度 (rSO2) 变化情况。结果两组患者T1T5时rSO2水平均较T0时明显升高, P0.05;观察组患者T2T5时CI值、r SO2、CVP及MAP水平明显高于对照组, P0.05。结论目标导向液体治疗应用于ASAⅡⅢ级胶质瘤患者手术切除中可有利于提高患者脑氧饱和度水平。 关键词： 胶质瘤; 脑氧饱和度; 目标导向液体; 手术切除; 收稿日期：2016-10-09 Application Value of Goal-directed Fluid Therapy Intraoperative Regional Cerebral Oxygen Saturation (rSO2) of ASA Ⅱ～Ⅲ Grade Glioma Patients XU Hui PLA 425 Hospital; Abstract： Objective To explore the application value of goal-directed fluid therapy for ASAIⅡgrade glioma patients treated with surgical resection, and the impact on hemodynamics and cerebral oxygen saturation, and to provide security for patients’safety during surgery.Methods Clinical operation of 86 patients with ASAⅡⅢglioma were retrospectively analyzed.Among them, routine treatment was performed in the control group (43 cases) .Target-oriented liquid therapy group was the observation group (43 cases) .Hemodynamic indicators, cardiac index (CI) and brain oxygen saturation (r SO2) of the 2 groups 30 min before the surgery (T0) , 15 min (T1) after anesthesia, 60 min (T2) during surgery, 120 min (T3) during surgery, 180 min (T4) during operation were measured.Results r SO2levels of the 2 groups during T1T5were significantly higher than those at T0, P0.05;CI value, r SO2, CVP and MAP levels in the observation group during T2T5were significantly higher than the control group, P0.05.Conclusion Goal-directed fluid therapy in ASAIⅡgrade glioma patients can improve r SO2level in brain. Keyword： Glioma; Brain oxygen saturation (rSO2) ; Goal-oriented liquid; Surgery; Received： 2016-10-09 因颅内肿瘤患者病变部位与其周围脑组织于手术期间难以发生机械性或缺氧性损伤, 同时因患者手术前需长时间禁食