腹腔置管灌洗在急性胰腺炎治疗中的临床意义.docVIP

精品论文 参考文献 腹腔置管灌洗在急性胰腺炎治疗中的临床意义 吴锐 　　（四川省什邡市人民医院 四川 什邡 618400） 　　【摘要】 目的：探讨早期腹腔置管灌洗(LPLD)在急性胰腺炎(AP)治疗中的临床意义。方法：选择我院2013年01月至2014年12月收治的SAP患者50例，随机分为灌洗组(25例)和常规治疗组(25例)。两组均进行胃肠道减压，禁食禁水，抑制胰腺分泌，抑酸，补液，对症等治疗，而灌洗组单独进行早期腹腔置管灌洗。对比两组治疗前、治疗第3天、第7天的C反应蛋白(CRP)水平、中性粒细胞（NE）水平；两组发生多器官功能障碍综合征(MODS)的器官数和全身炎症反应综合征(SIRS)持续时间以及死亡率。结果：两组CRP、NE值差异治疗前无统计学意义(Pgt;0.05)，治疗第3天两组存在一定差异(Plt;0.05)，第7天两组比较存在很明显差异(Plt;0．01)；对比两组发生MODS的个数、SIRS持续时间和死亡率也存在差异(Plt;0.05)。结论：早期腹腔置管灌洗术可以有效减少SAP的并发症和病死率。 　　【关键词】 腹腔灌洗；急性胰腺炎 　　【中图分类号】R576 【文献标识码】A 【文章编号】2095-1752（2016）23-0205-02 　　【Abstract】Objective To explore the clinical significance of peritoneal lavage and drainage (LPLD) in the early treatment of acute pancreatitis (AP). Methods Retrospective analyzed of 50 cases of SAP patients with the clinical data in our hospital from January 2013 to December 2014, including two randomly distributed groups: one with 25 cases as lavage group and 25 cases with conventional treatment as the other group. Two groups received the same treatment such as gastrointestinal decompression, prohibiting drinking water, inhibiting pancreatic secretion, acid suppression, fluid infusion, expectant treatment, etc.; whereas early peritoneal lavage was performed in the lavage group. The effect was compared before the treatment, on the 3rd day and the 7th day of the level of C reactive protein (CRP) and neutrophils(NE), the number of case occurrences of multiple organ dysfunction syndrome (MODS) , the duration of systemic inflammatory response syndrome (SIRS) as well as the mortality rate. Results The difference of the two groups had no obvious statistical significance (Pgt; 0.05) on the value of CRP and NE before the treatment; the two groups had some differences(Plt;0.05) on the 3rd day of the treatment; there were some obvious differences (Plt;0.01) between the two groups on the 7th day of the treatment; comparing the two groups, there were some differences (Plt;0.05) on the case number o