茵栀黄口服液辅助治疗对新生儿黄疸、胆红素及黄疸指数的影响.docVIP

精品论文 参考文献 茵栀黄口服液辅助治疗对新生儿黄疸、胆红素及黄疸指数的影响 陈 杰1 郑承宁2 陈飒英2 叶 芳1 王 琳 1 　　（中日友好医院 100029） 　　【摘 要】目的：研究茵栀黄口服液辅助治疗对新生儿黄疸、胆红素及黄疸指数的影响。方法：选择新生儿黄疸患儿120例为研究对象，采用随机数字表法分为观察组和对照组各60例，观察组患儿接受茵栀黄口服液辅助蓝光照射治疗，对照组患儿接受蓝光照射治疗，比较两组患儿的整体疗效、胆红素水平以及黄疸指数。结果：①治疗效果：观察组有效率（98.33%）明显高于对照组（78.33%），差异有统计学意义（x2=11.644, P=0.001）；②临床症状与体征情况：治疗后3d、5d和7d时，观察者患者的血清胆红素水平明显低于对照组，黄疸消退时间以及住院时间明显短于对照组，差异有统计学意义（t分别为-12.061，-15.800，-17.079，-7.809，-9.380，P均lt;0.05）；③黄疸指数：治疗后1d、3d、5d、7d时，观察者患者的黄疸指数低于对照组，差异有统计学意义（t分别为-0.377，-3.347，-5.270，-7.809，-9.380，P均lt;0.05）。结论：茵栀黄口服液联合蓝光照射治疗有助于降低血清胆红素水平和黄疸指数，缩短黄疸时间，提高治疗效果。。 　　【关键词】新生儿黄疸；茵栀黄口服液；胆红素；黄疸指数 　　【中图分类号】R722.17 【文献标识码】B 【文章编号】1003-5028（2015）6-0418-02 　　【Abstract】Objective: To study the effect of Yinzhihuang oral liquid injection on adjuvant therapy neonatal jaundice, bilirubin and jaundice index.Methods:120 cases patients with neonatal jaundice were divided into observation group and the control group, the observervation group received Yinzhihuang oral liquid combined with blue light therapy, control group received light therapy.Then overall effect,bilirubin levels and jaundice index were compared.Results:① Treatment effect:observation group efficient (98.33%)was significantly higher than that of control group (78.33%) （x2=11.644, P=0.001）; ②Clinical symptoms and signs: 3 d, 5 d and 7 d after treatment, the observation group serum bilirubin levels,were significantly lower than the control group, duration of jaundice and hospital stay time were significantly shorter than the control group （t were-12.061，-15.800，-17.079，-7.809，-9.380，all P lt;0.05）; ③Jaundice index:after treatment 1d, 3d, 5d, 7d, the observation group jaundice index were significantly lower than the control group（t were-0.377，-3.347，-5.270，-7.809，-9.380,all Plt;0.05）. Conclusion: Yinzhihuang oral liquid combined with blue light therapy is helpful to reduce serum bilirubin levels and jaundice index, shorten the time jaundice, improve overall efficacy. 　　【Keywords】Neonatal jaundice; Yinzh