珠海市斗门区农村居民血脂异常及与慢性非传染性疾病聚集性研究.docVIP

珠海市斗门区农村居民血脂异常及与慢性非传染性疾病聚集性研究 第30卷第4S期 2009年8月 中山大学(医学科学版) JOURNALOFSUNYAT—SENUNIVERSITY(MEDICALSCIENCES) V0l_30No.4S Aug.2009 珠海市斗门区农村居民血脂异常及与慢性非传染性 疾病聚集性研究 金莉子,黄日荷,邬伟明,陈剑,陈筱潮 (中山大学附属第五医院心内科,广东珠海519000) 摘要:【目的】分析珠海市斗门区农村居民血脂异常及与慢性非传染性疾病聚集性状况,为心脑血管疾病等慢性非传 染性疾病预防提供参考.【方法】按照分层随机抽样原则随机抽取斗门区两镇4个自然村,对其农村居民进行入户调查, 体检,分析血脂异常分布情况与糖尿病,高血压,肥胖,高尿酸血症的关系及相关危险因素.【结果】调查人群高胆固醇血症 (TC),高甘油三酯血症(TG),高低密度脂蛋白血症(LDL—C)和低高密度脂蛋白血症(HDL—C)的患病率分别为41.8%,15.3%, 67.5%及0.2%,高Tc,高LDL—C和女性高TG的患病率均随着年龄的增长而增高,并具有阶段性特点:血脂异常与高血压,糖 尿病,肥胖,血尿酸异常等疾病具有明显聚集性,女性显着于男性,Logistic逐步回归分析显示Tc异常患病率与年龄和腹型 肥胖正相关,与高血压家族史,吸烟负相关:TG异常患病率与超重肥胖和腹型肥胖正相关,LDL.C异常患病率与年龄和腹 型肥胖正相关.【结论】斗门区农村居民血脂异常患病率均较高,且女性显着于男性,必须引起足够重视,防治重点应采取点 面结合方式,加强对群体宣传和重点人群干预,控制肥胖,减少血脂异常及心血管疾病的发生. 关键词:血脂异常;非传染性疾病;患病率;危险因素 中图分类号:R54文献标识码:A文章编号:1672.3554(2009)4S一0151—04 InvestigationonStatusofLipidDisordersandChronicNoninfectiousDiseases AggregationinDoumenRuralAreaofZhuhaiCity JINLi—zi,HUANGRi-he,WUWei—ming,CHENJian,CHENXiao—chao Abstract:【Objective】Toinvestigatethestatusoflipiddisordersandchronicnoninfectiousdiseasesaggregationindoumen ruralareaofZhuhaicityandprovidereferencetopreventchronicnoninfectiousdiseaseslikecardio—cerebraldisease.【Methods】 FourvillagesintwotownsofDoumenweresampledthroughstratifiedrandomizedsampling,andinformationoftheresidentswas collectedbyinvestigate,physicalexamination,andlaboratorytest,thenanalyzedtheriskfactorsoflipiddisorderandthe relationshipwithdiabetesmellitus,hypertension,obesity,hyperurieaemia.【Results】Themorbidityratesofhypercholestemlemia, hypertriglyceridemia,highLDL—C,lowHDL—Cwere41.8%,15.3%,67.5%and0.2%separately.Bothinmenandwomen,the ratesofhypercholesterolemiaandhighLDL?Cwentupwiththeage,butonlyinfemale,therateofhypertriglyceridemiawentup, andtherewereaggregationbetweenlipiddisordersandhypertension,diabetesmellitus,obesity,hyperurieaemia.,especiallyin female,logisticregressionanalysisshowedthatTCdisorderratewaspositivecorrelationwithageandcentralobesity,itwas negativecorrelationwithhype~ensionfamilyhistoryandsmoking