动态表情情绪识别相关脑区fMRI研究.docVIP

动态表情情绪识别相关脑区fMRI研究 　　【摘 要】目的：利用事件相关的功能核磁共振成像技术研究健康汉族女性对动态表情的识别情况并探讨其神经基础。方法：利用1.5T功能核磁共振成像系统检测13名女性健康受试者识别悲伤、喜悦及中性动态表情视频时的脑部反应。图像数据经SPM2软件处理和统计分析，获得脑区激活图。结果：与识别十字架相比，识别中性表情激活左额中回、双侧中央前回、右侧杏仁核、左顶下小叶、右中央后回以及丘脑等。与识别中性表情相比，识别喜悦表情激活右额内侧回、右额上回、右额中回、右前扣带回、左胼胝体下回、右枕上回、右枕下回、左枕中回及右颞上回等脑区，而识别悲伤表情激活左额内侧回、右额中回、左颞下回以及左颞上回等脑区。结论：面孔加工及动态表情的识别由脑内一个分布式神经网络所调控，其中额内侧回参与多种情绪的加工，可能是情绪加工的共同通路，而颞上回主要负责面部动态特征的加工。 　　【关键词】 面孔；动态表情；视频刺激；实验室研究；功能核磁共振成像；神经影像学 　　中图分类号：B846.2、R445.2 文献标识码：A 文章编号：1000-6729(2007)08-00558-05 　　 　　Neural Substrates for Explicit Recognition of Dynamic Facial Expression by fMRI 　　DU Jing－Lun，YAO Zhi－Jian?@，XIE Shi－Ping，et al. 　　Psychiatry Department，Affiliated Nanjing Brain Hospital，Nanjing Medical University，Nanjing 210029 　　【Abstracts】 Objective: To explore neural correlates for the recognition of facial expression videos using event－related functional magnetic resonance imaging.Methods:Thirteen right－handed healthy Chinese women underwent blood oxygen level dependent (BOLD) fMRI voluntarily while recognizing happy, sad, neutral emotional faces and fixation cross videos.Results:In comparison with fixation cross, recognition of neutral faces activated the left middle frontal gyrus, the bilateral precentral gyrus, the right amygdala, the left parahippocampal gyrus, the right postcentral gyrus and the left thalamus. In comparison of neutral faces recognition, the recognition of happy faces elicited increased activation in the right medial frontal gyrus, the right superior frontal gyrus, the middle frontal gyrus, the right anterior cingulated gyrus, the left subcallosal gyrus, the right superior occipital gyrus, the left middle occipital gyrus and the right superior temporal gyrus; while the recognition of sad faces activated the left medial frontal gyrus, the right middle frontal gyrus, the left inferior temporal gyrus and the left superior temporal gyrus.Conclusion:This study indicates that the recognition of facial expression is mediated by a distributed corti