《宫颈癌讲课》课件.pptVIP

Thank You Student: Shamsiya Mentor: Maynur From Oncology department Cervical Cancer 宫颈癌 Student: Shamsiya Mentor: Maynur From Oncology department Cervix Lower part of the uterus Connects the body of the uterus to the vagina (birth canal) Source: American Cancer Society Statistics 10,520 new cases in the U.S. this year 3,900 will die 50% are diagnosed between ages 35 and 55. 20% at the age of 65 or over. Rarely occurs in women younger than 20 Noninvasive is four times more common 74% decrease in deaths between 1955 and 1992 in the U.S. Death rate continuous to decline by 2% a year Source: American Cancer Society Three Types Squamous cell Carcinomas Cancer of flat epithelial cell 80% to 90% Adenocarcinomas Cancer arising from glandular epithelium 10% - 20% Mixed carcinoma Features both types Cervical Cancer Begins in the lining of the cervix Cells change from normal to pre-cancer (dysplasia) and then to cancer Risk Factors Human papillomavirus infection (HPV) – Primary factor HPV 16, HPV 18, HPV 31, HPV 33, HPV 45 50% are caused by HPV 16 AND 18 Sexual behavior Smoking HIV infection Chlamydia infection Diet Oral contraceptives Multiple pregnancies Low socioeconomic status Diethylstilbestrol (DES) Family history Source: American Cancer Society Signs and Symptoms Vaginal bleeding Menstrual bleeding is longer and heavier than usual Bleeding after menopause or increased vaginal discharge Bleeding following intercourse or pelvic exam Pain during intercourse Source: American Cancer Society Diagnosis Cervical Cytology (Pap Test) Cells are removed from the cervix and examined under the microscope. Can detect epithelial cell abnormalities Atypical squamous cells Squamous intraepithelial lesions Squamous cell carcinoma (likely to be invasive) Source: American Cancer Society Diagnosis Addi