罗丹明染料合成及光谱性能研究.docVIP

罗丹明染料合成及光谱性能研究 　　摘要: 以带羧基、甲基的苯甲醛以及Ｎ,Ｎ-二乙基间氨基苯酚为原料,合成了罗丹明荧光染料,经酸催化缩合得到目标产物.该法避免了常规合成方法中5-位和6-位异构体混合物的产生， 减少了繁琐的分离纯化工序, 获得了单一的产物，从而降低了制备成本.光谱性能测试的结果表明，通过该方法合成出的化合物，其摩尔消光系数在不同溶剂中保持稳定，使化合物对溶剂环境的依赖性大大降低，这是由于该方法合成的罗丹明染料无异构体生成，因此没有醌式和内脂式的互变.[JP]? 　　关键词: 合成；光谱性能；罗丹明荧光染料；Ｎ,Ｎ-二乙基间氨基苯酚；苯甲醛? 　　中图分类号:TQ 613 文献标志码:A 文章编号:1672-8513(2011)03-0213-04 　　?? 　　The Synthesis of Rhodamine Dyes and Their Spectral Effects 　　 　　WANG Jiong, ZHANG Li?zhu, YANG Qin?jing, HU Jun 　　? 　　(Key Laboratory of Ethnic Medicine Resources Chemistry,State Ethnic Affairs Commission Ministry of Education,?School of Chemistry and Biotechnology,Yunnan University of Nationalities, Kunming 650031, China) 　　 　　Abstract: Rhodamine derivatives were synthesized with benzaldehyde instead of acidanhydride as raw materials. The normal rhodamine dyes were synthesized by 3-diethylaminophenol and isobenzofuran-1,3-dione, but this synthesis process was burdensome and the process of separation and purification was difficult. The product of the novel synthesis method was sole, avoiding the production of 5 and 6 isomer mixture in the normal synthesis process of rhodamine dyes so that the burdensome processes of separation and purification were greatly reduced, and the cost of production was saved. The synthesis of the two rhodamine derivatives was convenient and the yield was satisfactory. The results of spectrum properties show the extinction coefficients remaining stable in different solutions, because products from this synthesis method have no 5 isomers and transform between quinone form and spirolactam form. So the products are insensitive to the environment.? 　　Key words: synthesis;spectrum properties;Rhodamine dyes;N，N?diethylamionphenol;benzaldehyde 　　 　　用N-烷基-m-氨基酚与过量的邻苯二甲酸酐熔化缩合制得罗丹明染料是传统的合成方法［1］，邻苯二甲酸酐通常以2.0~2.5倍的理论用量来保证一定的产率, 并在后处理过程中采用碱溶液除去这些过量的酸酐，但这一操作并不合适，因过量的酸酐很难完全除去，一般需要几天的操作.如果降低酸酐的用量，这时反应过程中的邻苯二甲酸酐和N-烷基-m-氨基酚又不能保持熔融状态，反应结束后生成的副产物增加，在后处理时产生较多的排放废物，同时反应过程操作困难，产率降低.此外，用邻苯二甲酸酐与间氨基酚反应的传统方法生成的是?5-?