益气活血利水中药辅助雷单抗联合激光光凝治疗黄斑水肿临床观察.docVIP

益气活血利水中药辅助雷珠单抗联合激光光凝治疗黄斑水肿临床观察 　　[摘要] 目的 观察益气活血利水中药辅助雷珠单抗联合激光光凝治疗黄斑水肿的临床疗效。 方法 回顾性研究视网膜分支静脉阻塞（BRVO）继发黄班水肿（ME）患者60例（60只眼），随机分为两组。治疗组30例（30只眼），采用雷珠单抗玻璃体腔注射联合视网膜激光光凝，再服用益气活血利水中药，每日1剂，水煎分2次服，14 d为1个疗程，根据患者情况，每疗程之间相隔3～5 d，连用3个月；对照组30例（30只眼）采用雷珠单抗玻璃体腔注射联合视网膜激光光凝，不服用中药煎剂。在治疗后1周、1个月、2个月、3个月、6个月观察比较患眼最佳矫正视力（BCVA）、黄斑中心区视网膜厚度（CMT）及并发症。 结果 在治疗1周、1个月时，治疗组与对照组的BCVA、CMT比较，差异均无统计学意义（P0.05）。治疗2个月、3个月、6个月时，两组BCVA、CMT比较，差异均有统计学意义（P中国论文网 /6/viewhtm　　[关键词] 视网膜分支静脉阻塞；黄斑水肿；雷珠单抗；激光光凝；中药 　　[中图分类号] R774.5 [文献标识码] B [文章编号] 1673-9701（2016）21-0079-04 　　[Abstract] Objective To observe the clinical effect of Yiqi Huoxue Lishui Chinese medicine with ranibizumab and photocoagulation in the treatment of macular edema. Methods Retrospectively analyzed the 60 eyes of 60 patients who were diagnosed branch retinal vein occlusion（BRVO） related macular edema（ME）， they were divided into two groups randomly. The 30 eyes of 30 patients of the treatment group were treated with ranibizumab and photocoagulation， and with Yiqi Huoxue Lishui Chinese medicine. The prescription was daily dose， water frying and 2 times one day， 14 days was one treatment course. According to patients condition， treatment courses interval was 3 to 5 days and lasted for 3 months. The 30 eyes of 30 patients in control group were treated with ranibizumab and photocoagulation. The best corrected visual acuity（BCVA）， central macular retinal thickness（CMT） and complications between the two groups were compared after treatment （1 week， 1 month， 2 months， 3 months， 6 months）. Results At 1 week and 1 month after treatment， the difference of BCVA between two groups had no statistically significant（P0.05）， and so did the CMT. At 2 months， 3 months and 6 months after treatment， the differences of BCVA and CMT between two groups had statistically significant（P 　　1 资料与方法 　　1.1 一般资料 　　回顾性研究2014年1月～2015年1月在我院眼底病三病区诊治的视网膜分支静脉阻塞（branch retinal vein occlusion，BRVO）继发ME患者60例（60只眼），其中男32例，女28例，年龄40～70岁。随机分为两组，治疗组30例（30只眼）应用雷珠单抗玻璃体腔注射联合视网膜激光光凝，