PEGPEGJ联合PTCD治疗对恶性阻塞性黄疸患者营养状态和肝脏功能影响.docVIP

PEGPEGJ联合PTCD治疗对恶性阻塞性黄疸患者营养状态和肝脏功能影响 　　[摘要] 目的 探讨经皮胃/空肠造瘘术（PEG/J）联合经皮经肝穿刺胆道引流术（PTCD）治疗对恶性阻塞性黄疸患者营养状态和肝脏功能的影响。 方法 将河北大学附属医院2013年6月～2015年6月收治的56例恶性阻塞性黄疸患者随机分为对照组和联合组，各28例，其中对照组实施PTCD进行治疗，联合组在对照组的基础上实施PEG/J进行治疗，比较术后患者营养状态和肝脏功能，以及并发症情况。 结果 术前两组患者总蛋白（TP）、白蛋白（Alb）、转铁蛋白（TRF）水平比较差异无统计学意义（P 0.05），术后15 d均显著升高（P 0.05），术后15 d均显著降低（P 0.05）。 结论 PEG/J联合PTCD可有效改善恶性阻塞性黄疸患者的营养状态和肝脏功能，且并发症少，疗效显著，值得临床推广使用。 　　[关键词] 经皮胃造瘘术；恶性阻塞性黄疸；经皮经肝穿刺胆道引流术；营养状态；肝脏功能 　　[中图分类号] R575 [文献标识码] A [文章编号] 1673-7210（2016）08（b）-0134-04 　　[Abstract] Objective To discuss the effect of percutaneous endoscopic gastrostomy （PEG/J） combined with percutaneous transhepatic cholangial drainage （PTCD） on nutritional status and liver function in patients with malignant obstructive jaundice. Methods Fifty-six cases of patients with malignant obstructive jaundice treated in the Affiliated Hospital of Hebei University from June 2013 to June 2015 were randomly divided into control group and combination group， with 28 cases in each group. The control group was treated with PTCD， while the combination group was treated with PEG/J based on the control group. The nutritional status and liver function after operation and complications were compared between the two groups. Results The differences in the total protein （TP）， albumin （Alb）， transferrin （TRF） levels before operation between the two groups were not statistically significant （P 0.05）， which were significantly increased after 15 d of operation （P 0.05）， which were significantly decreased after 15 d of operation （P 0.05）. Conclusion PEG/J combined with PTCD can effectively improve the nutritional status and liver function in patients with malignant obstructive jaundice， with less complications and significant treatment effect， which is worthy of promotion and application in clinic. 　　[Key words] Percutaneous endoscopic gastrostomy； Malignant obstructive jaundice； Percutaneous transhepatic cholangial drainage； Nutritional status； Liver function 　　恶性阻塞性黄疸是胰腺、十二