中青年与老年直肠癌患者临床及病理特征差异分析.docVIP

中青年与老年直肠癌患者的临床及病理特征差异分析 　　【摘要】 目的：分析中青年与老年直肠癌患者的临床及病理特征差异。方法：将笔者所在医院2009年9月-2016年5月收治的105例直肠癌患者进行临床分析，47例为中青年组，58例为老年组；比较两组患者临床资料、病理特征和随访资料，观察其生存情况。结果：两组患者性别比例、Dukes分期、生存时间和三年生存率比较差异均无统计学意义（P0.05）；两组患者遗传史发生率、发病到确诊时间、便秘发生率、初始症状、肿瘤位置、组织学分类和分化情况比较差异均有统计学意义（P0.05）。结论：中青年患者病情发现晚、初始症状与老年患者差异较大，若及时诊治，两者预后则无明显差异。 　　【关键词】 中青年； 老年； 直肠癌； 病理特征 　　doi：10.14033/j.cnki.cfmr.2018.4.009 文献标识码 B 文章编号 1674-6805（2018）04-0019-02 　　Analysis of Clinical and Pathological Features of Middle-aged and Young Patients with Rectal Cancer/HUANG Lin.//Chinese and Foreign Medical Research，2018，16（4）：19-20 　　【Abstract】 Objective：To analyze the clinical and pathological characteristics of middle-aged and elderly patients with rectal cancer.Method：The clinical analysis of 105 patients with rectal cancer treated by our hospital from September 2009 to May 2016 were analyzed，and 47 cases were in the middle youth group.The 58 cases were aged The clinical data， pathological features and follow-up data of the two groups were compared to observe its survival.Result：There was no significant difference between the two groups of patients in terms of sex ratio， Dukes staging， survival time and three-year survival rate （P0.05）.There was a significant difference between the two groups of patients with the incidence of genetic history， the time of diagnosis，the incidence of constipation， initial symptoms， tumor location，histological classification and differentiation （P0.05）.Conclusion：The prognosis of young and middle-aged patients is significantly different from that of elderly patients， and the prognosis of the two patients is no significant difference. 　　【Key words】 Chinese youth； Old age； Rectal cancer； The pathological features 　　First-author’s address：Chengdu Tianfu New District People’s Hospital，Chengdu 610213，China 　　直?c癌是一种恶性肿瘤，在西方国家发生率较高，所占比例为所有成年癌症的5%左右，其致死率也不容小觑。随着时代不断进步，人类的生活方式和饮食习惯发生巨大变化，而我国的直肠癌发生率也逐年递增，每年的新增病例有十万左右，而男性所占比例在女性患者之上。直肠癌主要以60岁以上的老年人为高发群体，其中70岁以上老年人的发生率尤为突出。根据最新资料显示，近几年我国直肠癌患者逐渐发