定喘汤治疗哮喘慢性持续期疗效及不良反应分析.docVIP

定喘汤治疗哮喘慢性持续期疗效及不良反应分析 　　[摘要] 目的 研究定喘汤治疗哮喘慢性持续期的疗效及不良反应。 方法 研究对象为整群选取2013年4月―2014年5月该院收治的哮喘慢性疾病患者136例，随机法分为干预组（n=68）和对照组（n=68），所有患者给予糖皮质激素长效β2受体激动剂吸入治疗，干预组在此基础上加用定喘汤煎服，持续治疗3个月，比较其疗效及不良反应。 结果 干预组总有效率89.7%与对照组72.1%比较差异有统计学意义（P0.05）。 结论 采用定喘汤治疗哮喘慢性持续期患者能显著缓解哮喘症状，提高其生活质量，疗效好，不良反应少。 　　[关键词] 定喘汤；哮喘；持续期；不良反应 　　[中图分类号] R5 [文献标识码] A [文章编号] 1674-0742（2016）02（c）-0144-02 　　Observation on Curative Effect and Adverse Reaction of Asthma-Reliving Decoction in Treatment of Asthma Chronic Persistent Period 　　LI Hai-gang 　　Department of respiration， The First Affiliated Hospital of Henan University of Traditional Chinese Medicine， 450000 China 　　[Abstract] Objective To research the curative effect and adverse reaction of asthma-reliving decoction in treatment of asthma chronic persistent period. Methods 136 cases of patients with asthma chronic disease admitted and treated in our hospital from April 2013 to May 2014 were selected as the research object and randomly divided into two groups with 68 cases in each， all patients were given inhaled treatment of glucocorticosteroid and long-β 2-agonist， the intervention group were given asthma-reliving decoction on this basis for 3 months， the curative effect and adverse reaction of the two groups were compared. Results The difference in the total effective rate between the intervention group and the control group had statistical significance，（89.7% vs 72.1%），（P0.05）. Conclusion Asthma-reliving decoction in treatment of patients with asthma chronic persistent period？can obviously relieve asthma symptoms and improve the quality of life with good curative effect and few adverse reactions. 　　[Key words] Asthma-reliving decoction； Asthma； Persistent period； Adverse reaction 　　哮喘是在气道过敏原或感染等因素刺激下产生支气管可逆性气道狭窄的慢性气道炎症性疾病，临床主要表现为胸闷、气急、咳嗽、呼吸困难等症状，一般在清晨和夜间加重[1]。采用西医治疗虽能及时改善症状，但易复发且不良反应较大，目前中医治疗哮喘成为诸多学者研究的热点[2]，该研究于2013年4月―2014年5月间临床观察了定喘汤对哮喘慢性持续期患者的治疗效果，现报道如下。 　　1 资料与方法 　　1.1 一般资料 　　研究对象为整群选取2013年4月―2014年5月该院收治的哮喘慢性疾病患者136例，所有患者均经临床诊断和检查确诊，符