应用MSCTA对急性脑梗死与颈动脉粥样硬化关系研究.docVIP

应用MSCTA对急性脑梗死与颈动脉粥样硬化关系研究 　　【摘要】 目的：应用MSCTA检查分析急性脑梗死与颈动脉粥样硬化的关系。方法：对95例急性脑梗死患者行颈动脉MSCT血管成像检查，根据诊断分为脑梗死灶侧颈动脉组（研究组）和对照侧颈动脉组（对照组），分析脑梗死病灶侧颈动脉斑块的性质及管腔狭窄程度。结果：研究组95支颈动脉中，80支（84.2%）出现粥样硬化，对照组95支颈动脉中，有40支（42.1%）发生粥样硬化，两组比较差异有统计学意义（P0.01）。80支颈动脉粥样硬化中，软斑块28支，混合斑块18支，钙化斑块34支，易损斑块占57.5%（46/80），钙化斑块占42.5%（34/80）；管腔狭窄程度分布如下：正常30支，轻度狭窄30支，中度狭窄9支，重度狭窄4支，闭塞7支，中度及以上狭窄者占25.0%（20/80），轻度狭窄者占37.5%（30/80）。结论：病灶同侧颈动脉粥样硬化是急性脑梗死的重要危险因素，而易损斑块的存在会提高患病风险；MSCTA对早期筛查及诊断颈动脉粥样硬化斑块具有很好临床应用价值。 　　【关键词】 脑梗死； 颈动脉； 动脉粥样硬化； X线计算机； 体层摄影术； 血管成像 　　【Abstract】 Objective：To investigate the relationship between carotid atherosclerosis and acute cerebral infarction.Method：A total of 95 cases of acute cerebral infarction patients with carotid artery MSCT angiography examination， according to the diagnosis，the patients were divided into cerebral infarction in the carotid artery （study group） and the contralateral normal carotid artery （control group）， cerebral infarction lesions of the carotid artery stenosis and the degree of stenosis was analyzed.Result：In the study group of 95 carotid artery，80（84.2%）cases had atherosclerosis，in the control group of 95 carotid artery，40（42.1%）cases had atherosclerosis，two groups were significantly different （P0.01）.80 cases of carotid atherosclerosis，28 cases of soft plaque，18 cases were mixed plaque，34 cases were calcified plaque，46 cases were vulnerable plaques， accounting for 57.5%（46/80），calcified plaque accounted for 42.5%（34/80）.The stenosis of the lumen was as follows：30 normal， 30 cases were mild stenosis，9 cases were moderate stenosis，4 cases of severe stenosis，7 cases of occlusion.The total of 20 patients with moderate or more stenosis accounted for 25.0%（20/80），and mild stenosis accounted for 37.5%（30/80）.Conclusion：Carotid atherosclerosis is an important risk factor for acute cerebral infarction，and the presence of vulnerable plaque can increase the risk of acute cerebral infarction.MSCTA has good clinical application value in early screening and diagnosis of ca