平胃散联合奥美拉唑治疗幽门螺杆菌相关性消化性溃疡临床观察.docVIP

平胃散联合奥美拉唑治疗幽门螺杆菌相关性消化性溃疡临床观察 　　摘要：目的观察分析平胃散联合奥美拉唑治疗幽门螺杆菌相关性消化性溃疡的临床疗效。方法选取140例消化性溃疡患者作为研究对象，采用数字表法随机平分成观察组和对照组各70例。对照组采用奥美拉唑+克拉霉素+阿莫西林治疗，观察组采用平胃散联合奥美拉唑治疗，观察两组治疗效果及Hp 的根除情况。结果观察组治疗有效率（94.29%）、组幽门螺杆菌根除率（88.57%）明显高于对照组（P0.05）。结论平胃散联合奥美拉唑治疗幽门螺杆菌相关性消化性溃疡，消化道症状缓解快，Hp 根除率高，临床疗效确切。 　　关键词：平胃散；消化性溃疡；幽门螺杆菌；奥美拉唑 　　Clinical Observation of Pingwei Powder Combined with Omeprazole in the Treatment of Helicobacter Pylori Associated Peptic Ulcer 　　SHEN Zhong-neng 　　(Fushun County Hospital of Traditional Chinese Medicine,Zigong 643200,Sichuan,China) 　　Abstract：ObjectiveTo observe the clinical effect of Pingwei Powder Combined with omeprazole on Helicobacter pylori associated peptic ulcer. Methods140 cases of peptic ulcer patients as the research object, randomly divided into observation group and control group with 70 cases in each. The control group used omeprazole, clarithromycin and amoxicillin treatment, the observation group with Pingwei Powder Combined with omeprazole treatment, to observe the effect of therapy effect of two group and Hp. ResultsIn the observation group, the treatment efficiency (94.29%), group of eradication rate of Helicobacter pylori (88.57%) was significantly higher than the control group (P0.05). ConclusionPingwei Powder Combined with omeprazole in the treatment of Helicobacter pylori associated peptic ulcers, gastrointestinal symptoms, Hp eradication rate is high, clinical curative effect. 　　Key words：Pingweisan;Peptic ulcer; Helicobacter pylori;Omeprazole消化性溃疡（Peptic ulcer，PU）是胃溃疡（GU）和十二指肠球部溃疡（DU）的总称，是临床消化系统常见病和多发病，主要由幽门螺杆菌感染引起，患者常表现为剑突下疼痛、反酸、呃逆、嗳气等不适，严重者可发生出血及溃疡穿孔，对患者生命健康安全构成极大威胁[1]。消化性溃疡的药物治疗方法较多，但幽门螺杆菌根除率较低，溃疡极易反复发生，增加患者的痛苦。本院采用平胃散联合奥美拉唑治疗幽门螺杆菌相关性消化性溃疡，取得了满意的效果，现报告如下。 　　1资料与方法 　　1.1一般资料 研究对象为2012年6月~2013年12月，来我院就诊的140例消化性溃疡患者。所有患者均有上腹部胀痛不适、反酸、嗳气、呃逆病史，均经胃镜检查，符合消化性溃疡诊断标准。中医诊断参考郑筱萸[2]中药新药临床研究指导原则。将140例患者随即分为两组，观察组70例中男39例，女31例，年龄24~51岁，平均年龄（37.5±1.29）岁；其中胃溃疡41例，十二指肠球部溃疡29例。对照组70例中男42例，女28例，年龄26~54岁，平均年龄（36.9±1.56）岁；其中胃溃疡38例，十二指肠球部溃疡32例。两组患者性别、年龄