急性胰腺炎检测降钙素原与及C反应蛋白价值分析.docVIP

急性胰腺炎检测降钙素原与及C反应蛋白价值分析 　　【摘要】 目的 分析评价急性胰腺炎患者检测降钙素原与C反应蛋白的临床诊断价值以及对治疗的意义。方法 84例急性胰腺炎患者， 按照随机双盲法分成急性胰腺炎感染组和急性胰腺炎非感染组， 各42例。另选择同期非急性胰腺炎健康人42例作为非急性胰腺炎健康人组。分别检测三组血清降钙素原和C反应蛋白水平， 并进行比较。结果 急性胰腺炎感染组患者降钙素原为（5.2±0.6）μg/L、急性胰腺炎非感染组为（1.8±0.5）μg/L、非急性胰腺炎健康人组为（0.7±0.3）μg/L， 急性胰腺炎感染组和急性胰腺炎非感染组患者降钙素原高于非胰腺炎健康人组， 差异具有统计学意义（P0.01）；急性胰腺炎感染组患者降钙素原高于急性胰腺炎非感染组患者， 差异具有统计学意义（P0.05）。急性胰腺炎感染组患者C反应蛋白为（171.6±26.8）mg/L、急性胰腺炎非感染组为（114.2±20.8）mg/L、非急性胰腺炎健康人组为（10.2±1.8）mg/L， 急性胰腺炎感染组和急性胰腺炎非感染组患者降钙素原高于非胰腺炎健康人组， 差异具有统计学意义（P0.01）；急性胰腺炎感染组患者降钙素原高于急性胰腺炎非感染?M， 差异具有统计学意义（P0.05）。结论 通过检测患者降钙素原和C反应蛋白能够客观的对急性胰腺炎进行早期诊断， 并且对患者感染的程度具有优良的敏感性， 可以对疾病的进展和预后情况做出有效的评价， 具有广泛的临床应用前景。 　　【关键词】 C反应蛋白；降钙素原；急性胰腺炎 　　DOI：10.14163/j.cnki.11-5547/r.2017.01.022 　　Analysis of value by procalcitonin and C-reactive protein detection in acute pancreatitis WANG Li. Department of Laboratory Medicine， Shenyang City Seventh People’s Hospital， Shenyang 110003， China 　　【Abstract】 Objective To analyze and evaluate clinical diagnostic value by procalcitonin and C-reactive protein detection in acute pancreatitis and their significance for treatment. Methods A total of 84 patients with acute pancreatitis were divided by random double blind method into acute pancreatitis infection group and acute pancreatitis non-infection group， with 42 cases in each group. There were 42 healthy people at the same period as non-acute pancreatitis healthy group. Serum procalcitonin and C-reactive protein levels were detected in all groups for comparison. Results The acute pancreatitis infection group had procalcitonin as （5.2±0.6） μg/L， which was （1.8±0.5） μg/L in the acute pancreatitis non-infection group and （0.7±0.3） μg/L in the non-acute pancreatitis healthy group. The acute pancreatitis infection group and the acute pancreatitis non-infection group had higher procalcitonin level than the non-acute pancreatitis healthy group， and the difference had statistical significance （P 　　【Key words】 C-reactive protein； Procalcitonin； Acute pancreatitis 　　急性胰腺