游离腓骨皮瓣重建放射性下颌骨坏死术后缺损临床效果研究.docVIP

游离腓骨皮瓣重建放射性下颌骨坏死术后缺损临床效果研究 　　【摘要】 目的：探讨游离腓骨（肌）皮瓣重建放射性下颌骨坏死术后缺损的效果。方法：将本院2016年5-12月收住的64例放射性下颌骨坏死患者，按照随机数字表法将患者分为对照组和观察组，各32例。对照组患者给予常规药物治疗，观察组患者给予游离腓骨（肌）皮瓣重建手术，将两组的治疗效果进行对比分析。结果：治疗后，观察组并发症发生率低于对照组，差异有统计学意义（P0.05）。治疗后，观察患者咬合情况、外形恢复情况、愈合情况以及皮瓣存活情况均优于对照组，差异均有统计学意义（P0.05）。出院随访3个月后，观察组患者的生命质量各项评分均高于对照组，差异均有统计学意义（P0.05）。结论：游离腓骨（肌）皮瓣重建手术对放射性下颌骨坏死患者有着极其重要的意义，可以降低患者并发症发生率，提高患者生命质量，具有实用价值，可临床推广。 　　【关键词】 游离腓骨（肌）皮瓣重建手术； 放射性下颌骨坏死 　　Clinical Effect Study of Free Fibula （Musculocutaneous） Flap on Reconstruction of Defects after Radiation-induced Osteonecrosis of Mandible/HONG Jinchao，QIU Fangsong，ZHENG Jun，et al.//Medical Innovation of China，2018，15（06）：001-004 　　【Abstract】 Objective：To investigate the effect of free fibula （musculocutaneous） flap on reconstruction of postoperative defects after radiation-induced osteonecrosis of mandible.Method：From May 2016 to December 2016，64 patients with radiation osteonecrosis of mandible were selected，according to the random digital table method，they divided into control group and observation group，32 cases in each group.The patients in the control group were treated with routine medicine，and the patients in the observation group were treated with free fibula （musculocutaneous） flap reconstruction，the therapeutic effects of the two groups were compared and analyzed.Result：After treatment，the incidence of complications in the observation group was lower than that in the control group，the difference was statistically significant（P0.05）.After treatment，the occlusal，shape recovery，healing and flap survival of the patients were better than those of the control group，the differences were statistically significant（P0.05）.After 3 months follow-up，the scores of quality of life in the observation group were higher than those in the control group，the differences were statistically significant（P0.05）.Conclusion：Free fibula （musculocutaneous） flap reconstruction is very important for radioactive mandibular necrosis，it can reduce the incidence of co