生长抑素联合奥美拉唑治疗上消化道出血临床效果分析.docVIP

生长抑素联合奥美拉唑治疗上消化道出血临床效果分析 　　【摘要】 目的：探讨生长抑素联合奥美拉唑治疗上消化道出血患者的临床效果。方法：选取50例诊断为上消化道出血患者，按照随机数字表法将患者分为对照组和治疗组，各25例。对照组采用奥美拉唑60 mg+0.9%氯化钠溶液100 mL静脉滴注，1次/d；治疗组在对照组治疗基础上采用生长抑素3 mg+0.9%氯化钠溶液48 mL，4 mL/h，持续泵注。评价两组的临床疗效，并记录有效止血时间、24 h再出血率，统计两组治疗期间的不良反应。结果：治疗后，治疗组患者总有效率为92.0%，明显高于对照组的68.0%（P0.05）；治疗组有效止血时间为（18.9±5.1） h，明显短于对照组的（30.7±6.9） h（P0.05）；治疗组24 h再出血率为4.0%，明显低于对照组的24.0%（P0.05）；治疗组的不良反应发生率为8.0%，明显低于对照组的36.0%（P0.05）。结论：采用奥美拉唑联合生长抑素治疗上消化道出血效果显著且安全，值得临床推广应用。 　　【关键词】 奥美拉唑； 生长抑素； 上消化道出血； 再出血 　　The Clinical Effect Analysis of Upper Gastrointestinal Hemorrhage with the Treatment of Somatostatin Combined with Omeprazole/ZHANG Cui-lu，LI Yan，LI Rui，et al.//Medical Innovation of China，2016，13（33）：090-092 　　【Abstract】 Objective：To investigate the clinical effect of Somatostatin combined with Omeprazole in the treatment of upper gastrointestinal bleeding.Method：50 cases were diagnosed as upper gastrointestinal bleeding，according to the random number table method they were divided into the control group and treatment group，each of 25 cases.The control group was used 60 mg Omeprazole +0.9% 100 mL Sodium Chloride Solution，intravenous infusion，1 time/d.The treatment group in the control group treatment based on the use of Somatostatin 3 mg+0.9% Sodium Chloride Solution 48 mL，4 mL/h，continuous pump injection.The clinical efficacy of the two groups was evaluated，and the effective hemostasis time and 24 h rehaemorrhagia rate were recorded，the adverse reactions during the treatment of the two groups were recorded.Result：After the treatment，the total effective rate in treatment group was 92.0%，significantly higher than 68.0% in control group（P0.05）.The effective hemostasis time in treatment group was （18.9±5.1） h，which was significantly shorter than （30.7±6.9） h in control group（P0.05）.The rate of rehaemorrhagia for 24 h in treatment group was 4.0%，which was lower than 24.0% in control group（P0.05）.The adverse reaction rate in the treatment group was 8.0%，which was significantly less than