滋肾调肝活血调周法对PCOS患者卵巢形态学影响初步临床研究.docVIP

滋肾调肝活血调周法对PCOS患者卵巢形态学影响初步临床研究 　　[摘要] 目的 ?^察滋肾调肝活血调周法、二甲双胍及两者联合用药治疗多囊卵巢综合征（PCOS）的临床疗效。 方法 将114例符合诊断标准的PCOS患者随机分为三组，中药组37例，西药组38例，中西药组39例，三组患者无显著差异，具有可比性。治疗3个疗程，观察临床疗效及治疗前后三组患者的卵巢体积（V）、卵泡数目（Fn）、卵巢间质面积/卵巢总面积比（S/A）、子宫内膜厚度（双层，En）的变化。 结果 西药组、中药组、中西药组有效率呈依次增高。治疗后三组V、Fn、S/A、En各自与治疗前比较，差异均有统计学意义（P0.05），中药组与中西药组V、Fn、S/A、En差异均有统计学意义（P0.05），西药组与中西药组V、Fn、S/A、En差异均有统计学意义（P0.05）。 结论 滋肾调肝活血调周法联合二甲双胍治疗PCOS可以取得较好疗效。 　　[关键词] 滋肾调肝活血调周法；二甲双胍；PCOS；中西医结合 　　[中图分类号] R711.75 [文献标识码] B [文章编号] 1673-9701（2018）10-0131-04 　　Preliminary study on the effect of Zishen Tiaogan Huoxue Tiaozhou recipe on ovarian morphology in patients with PCOS 　　YANG Zhi YE Liqun 　　Department of Gynecology， Ningbo Traditional Chinese Medicine Hospital， Ningbo 315000， China 　　[Abstract] Objective To observe the clinical effect of Zishen Tiaogan Huoxue Tiaozhou recipe， metformin and combination therapy on polycystic ovary syndrome（PCOS）. Methods 114 patients meeting the diagnostic criteria of PCOS were randomly divided into three groups， including 37 cases of traditional Chinese medicine group， 38 cases of western medicine group and 39 cases of integrated traditional Chinese and western medicine group. And there were no significant differences in the three groups of patients， which were comparable. The patients were treated for 3 courses. The clinical efficacy and the changes of ovarian volume （V）， follicles number（Fn）， ovarian interstitial area/total ovarian area ratio（S/A）， endometrial thickness（double layer， En） in the three groups before and after treatment were observed. Results The effective rate of western medicine group， traditional Chinese medicine group and integrated traditional Chinese and western medicine group was increased in turn. There were significant differences in V， Fn， S/A and En after the treatment compared with those before treatment in the three groups（P0.05）. There were significant differences in V， Fn， S/A and En between traditional Chinese medicine group and integrated traditional Chi