甲钴胺联合丹红注射液治疗老年糖尿病周围神经病变临床研究.docVIP

甲钴胺联合丹红注射液治疗老年糖尿病周围神经病变临床研究 　　[摘要] 目的 探讨分析甲钴胺联合丹红注射液治疗老年糖尿病周围神经病变的临床疗效。方法 选择144例原发性高血压患者，随机分为70例对照组和74例实验组，对照组采用甲钴胺治疗，实验组在对照组患者治疗的基础上联用丹红注射液，两组患者均进行为期四周的治疗，治疗期间均严格控制血糖。结果 治疗后，实验组患者的正中神经和腓总神经的运动神经传导速度与感觉神经传导速度均显著优于对照组（P0.05）。实验组和对照组治疗后的总有效率分别为91.89%，75.71%，实验组的总有效率显著高于对照组（P0.05）。结论 甲钴胺联合丹红注射液治疗老年糖尿病周围神经病变能显著提高患者的神经传导速度，疗效显著，不良反应小，值得临床推广。 　　[关键词] 糖尿病；老年；周围神经病变；甲钴胺；丹红注射液；联合用药 　　[中图分类号] R587 [文献标识码] A [文章编号] 1672-4062（2016）10（a）-0031-02 　　[Abstract] Objective To investigate and analyze the clinical curative effect of senile diabetic peripheral neuropathy of Mecobalamin Combined with Danhong injection in the treatment of. Methods A total of 144 patients with primary hypertension patients， randomly divided into for 70 cases of control group and 74 cases in the experimental group， patients in control group were treated with Mecobalamin， experimental group in the control of the patients in the treatment group on the basis of Danhong injection， two groups of patients were for a period of four weeks of treatment， during treatment are in strict control of blood glucose. Results After treatment， the motor nerve conduction velocity and sensory nerve conduction velocity were significantly higher in the experimental group than that in the control group（P0.05）. Experimental group and control group after treatment， the total effective rate was 91.89%， 75.71%， the total effective rate of the experimental group was significantly higher than that of the control group （P0.05）. Conclusion Mecobalamin Combined with Danhong injection in the treatment of elderly diabetic peripheral neuropathy can significantly improve patients with nerve conduction velocity， remarkable curative effect， less adverse reactions， it is worth clinical promotion. 　　[Key words] Diabetes； Elderly； Peripheral neuropathy； Mecobalamin； Danhong injection； Drug combination； 　　糖尿病周围神经病变是糖尿病常见的并发症之一，随着糖尿病病程的延长，该病的发病率会达到50%以上，是糖尿病患者主要的致残因素之一[1]。该病的主要临床表现为疼痛麻木、腹胀、出汗，严重影响患者的生活质量[2]。目前临床上对于已发生的神经病变的治疗方法以针灸、中药熏洗为主，并无特效疗