美托洛尔联合通心络胶囊治疗冠心病心绞痛临床观察.docVIP

美托洛尔联合通心络胶囊治疗冠心病心绞痛临床观察 　　[摘要] 目的 探讨美托洛尔联合通心络胶囊治疗冠心病心绞痛的效果。 方法 将68例冠心病心绞痛患者，采用随机数字表法分为观察组（联合治疗组）及对照组（美托洛尔组）。入院后所有患者均给予常规基础治疗，在常规治疗的基础上，对照组患者给予美托洛尔，观察组除美托洛尔外加用通心络胶囊。对比观察两组患者的临床疗效、心电图改变、24 h动态心电图变化。 结果 观察组患者的临床总有效率为88.24%，对照组为47.06%，两组差异有统计学意义（χ2=13.170，P=0.000）。观察组患者心电图改变的总有效率为94.12%，对照组为52.94%，两组差异有统计学意义（χ2=14.809，P=0.000）。观察组患者的动态心电图发作性ST-T改善情况与对照组相比更为显著（P0.05）。 结论 美托洛尔联合通心络胶囊治疗冠心病心绞痛，对患者症状的改善效果显著，效果可靠，值得推广。 　　[关键词] 冠心病心绞痛；通心络胶囊；美托洛尔；临床疗效 　　[中图分类号] R542.2 [文献标识码] A [文章编号] 1674-4721（2014）09（a）-0087-03 　　Clinical observation of metoprolol combined with Tongxinluo capsule in the treatment of angina pectoris of coronary heart diseases 　　XIAO Zhi-jie 　　Department of Vasculocardiology，Shangrao People′s Hospital of Jiangxi Province，Shangrao 334100，China 　　[Abstract] Objective To explore the curative effects of metoprolol combined with Tongxinluo capsule in the treatment of angina pectoris of coronary heart diseases. Methods 68 patients with angina pectoris of coronary heart diseases were allocated to an observation group （combined treatment group） and a control group （metoprolol group） based on a random number table.Patients were given regular treatment after admission.On the basis of the regular treatment，the control group was given metoprolol，and the observation group was further given Tongxinluo capsule.Clinical efficacy，changes of electrocardiogram and changes of 24-hour dynamic electrocardiogram between the two groups were compared and observed. Results The clinical total effective rate was 88.24% in the observation group and 47.06% in the control group and the difference was statistically significant （χ2=13.170，P=0.000）.The total effective rate of changes of electrocardiogram was 94.12% in the observation group and 52.94% in the control group，and the difference was statistically significant （χ2=14.809，P=0.000）.Improvement of paroxysmal ST-T of dynamic electrocardiogram in the observation group was more significant than that in the control group （P0.05）. Conc