长期间歇性小剂量利尿剂治疗慢性心衰临床效果分析.docVIP

长期间歇性小剂量利尿剂治疗慢性心衰临床效果分析 　　DOI：10.16662/j.cnki.1674-0742.2017.07.007 　　[摘要] 目的 剖析慢性心衰用长期间歇性小剂量利尿剂的疗效。方法 利用电脑随机双盲法，分组方便选取该院2014年9月―2016年3月期间接收的130例慢性心衰病例：实验与对照各65例。前者行长期间歇性小剂量利尿剂治疗，后者行长期持续服用利尿剂治疗。观察比较两组用药后病情的改善情况。结果 实验与对照两组的疗效比较差异无统计学意义（92.31% vs 87.69%），但前者用药后的电解质紊乱发生情况与再入院情况明显优于对照组（P0.05）；实验组不良反应发生率（6.15%）、患者满意度（95.38%）明显优于对照组（21.34%、76.92%）（P0.05）。 结论 对慢性心衰者施以长期间歇性小剂量利尿剂治疗，有助于降低疾病复发率，减少电解质紊乱发生风险。 　　[关键词] 慢性心衰；电解质紊乱；长期间歇性；利尿剂 　　[中图分类号] R541 [文献标识码] A [文章编号] 1674-0742（2017）03（a）-0007-03 　　Analysis of Clinical Effect of Long-term Intermittence Small-dose Diureticum in Treatment of Chronic Heart Failure 　　WANG Qian-xiang 　　Department of Cardiovascular Medicine， Wanyuan Central Hospital， Wanyuan， Sichuan Province， 636350 China 　　[Abstract] Objective To analyze the curative effect of long-term intermittence small-dose diureticum in treatment of chronic heart failure. Methods Convenient selection 130 cases of patients with chronic heart failure admitted and treated in our hospital from September 2014 to March 2016 were randomly divided into two groups with 65 cases in each， the experimental group adopted the long-term intermittence small-dose diureticum treatment， while the control group took the diureticum orally constantly for a long time， and the improvement of disease of the two groups was observed and compared. Results The difference in the curative effect between the two groups had no statistical significance，（92.31% vs 87.69%）， but the occurrence of electrolyte disturbances after medication and readmission rate were obviously better than that in the control group（P0.05）， and the incidence rate of adverse reactions and satisfactory degree in the experimental group were obviously better than those in the control group， （6.15%， 95.38% vs 21.34%， 76.92%）（P0.05）. Conclusion The long-term intermittent small-dose diureticum treatment for patients with chronic heart failure contributes to reducing the recurrence rate of diseases and reducing the occurrence risks o