阿奇霉素序贯疗法治疗小儿支原体肺炎分析.docVIP

阿奇霉素序贯疗法治疗小儿支原体肺炎分析 　　[摘要] 目的 探析阿奇霉素序贯疗法治疗小儿支原体肺炎的临床效果。方法 方便选取该院2014年1月―2016年2月收治的76例小儿支原体肺炎患儿，将其随机分为研究组和对照组，各为38例，研究组采取阿奇霉素序贯疗法，10 mg/（kg?d），1次/d，静脉滴注，连续治疗5 d，停药4 d后改为阿奇霉素干混悬剂，10 mg/（kg?d），1次/d，口服，连服3 d。对照组采取红霉素序贯疗法，25～30 mg/（kg.d），1次/d，静脉滴注，连续治疗5 d后改为红霉素片剂25～30 mg/（kg?d），3次/d，口服，连服7 d比较两组治疗效果及不良反应情况。结果 研究组患儿总有效率97.37%与对照组78.95%比较差异有统计学意义（P0.05）；研究组不良反应发生率15.79%与对照组28.95%比较差异明显，P0.05差异有统计学意义。结论 采取阿奇霉素序贯疗法治疗小儿支原体肺炎的效果明显，不良反应少，值得临床推广。 　　[关键词] 阿奇霉素；序贯疗法；小儿支原体肺炎；临床效果 　　[中图分类号] R725 [文献标识码] A [文章编号] 1674-0742（2016）09（a）-0111-03 　　[Abstract] Objective Of azithromycin sequential therapy in children with mycoplasma pneumonia clinical results. Methods Convenient selection our hospital in January 2014 ― February 76 cases of children with mycoplasma pneumonia in children admitted 2016， were randomly divided into study group and the control group， 38 cases， the study group taking azithromycin sequential therapy，10 mg/（kg?d），1 time a day， intravenous infusion for 5 consecutive days to 4 days after discontinuation of azithromycin suspension， 10 mg/（kg?d） once daily， oral， and even served three days. The control group taking erythromycin sequential therapy， 25～30 mg/（kg?d）， 1 time a day， intravenous infusion for 5 consecutive days to erythromycin tablets 25～30 mg/（kg?d）， 3 times a day， orally， for 7 days were compared therapeutic effects and adverse reactions. Results Patients of the study group the total efficiency 97.37% and control group was 78.95%， the difference was significant， P 0.05 were considered to be statistically significant； the incidence of adverse reactions of the study group was 15.79% and control group 28.95% compared， P 0.05 significant. Conclusion Take azithromycin sequential therapy in children with mycoplasma pneumonia obvious effect， less adverse reaction， worthy of promotion. 　　[Key words] Azithromycin； Sequential therapy； Mycoplasma pneumonia in children； Clinical effect 　　肺炎支原体肺炎是由于肺炎支原体引起的呼吸道感染症状，其主要的临床表现是肺炎、咽炎等症状，高发人群多为免疫系统功能低下者，例如儿童[1]。小儿支原体肺