阿奇霉素与红霉素治疗小儿支原体肺炎临床观察.docVIP

阿奇霉素与红霉素治疗小儿支原体肺炎临床观察 　　[摘要] 目的 观察阿奇霉素与红霉素治疗小儿支原体肺炎的临床效果。 方法 选取本院2011年11月～2013年3月收治的80例小儿支原体肺炎患儿，按照就诊序号将其随机分为A、B两组，A组患儿在常规治疗的基础上应用阿奇霉素治疗，B组患儿在常规治疗的基础上应用红霉素治疗，比较两组患儿的治疗效果。 结果 A组患儿的临床症状改善时间及住院时间均明显短于B组（P0.05）；A组患儿的不良反应发生率（7.5%）明显低于B组（60.0%）（P0.05）。 结论 阿奇霉素治疗小儿支原体肺炎有着比红霉素更好的临床效果，可以在临床上广泛推广。 　　[关键词] 小儿支原体肺炎；阿奇霉素；红霉素；临床疗效 　　[中图分类号] R722.13+5 [文献标识码] A [文章编号] 1674-4721（2013）11（a）-0072-02 　　Clinical observation of azithromycin and erthromycin in treatment of children with Mycoplasma pneumonia 　　HUANG Chao-hong 　　Department of Pediatrics，Maternal and Child Health Hospital of Ganzhou City in Jiangxi Province，Ganzhou 341000，China 　　[Abstract] Objective To observe the clinical effect of azithromycin and erythromycin in the treatment of children with Mycoplasma pneumonia. Methods 80 children with Mycoplasma pneumonia who were admitted to our hospital from November 2011 to March 2013 were randomly divided into group A and group B according to the treatment sequence number.Group A received azithromycin on the basis of basic treatment，group B received erythromycin on the basis of basic treatment.The treatment effect of the two groups was compared. Results The improvement time of clinical symptoms and hospitalization time of group A were shorter than that of group B（P0.05）；the incidence rate of adverse reactions of group A（7.5%） was lower than that of group B（60.0%）（P0.05）. Conclusion Azithromycin shows better clinical effect than erythromycin in the treatment of children with mycoplasma pneumonia and thus can be widely promoted in clinical practice. 　　[Key words] Mycoplasma pneumonia；Azithromycin；Erythromycin；Clinical efficacy 　　小儿支原体肺炎是儿科的常见疾病之一，多发生于5～15岁儿童，发病后患儿发热无定型或有明显的咳嗽、头痛等临床表现，X线下改变明显，大部分有单侧病变，有时病灶呈游走性，少数呈大叶性阴影。临床上治疗此病时在进行退热、补液及镇静等常规治疗的基础上，多应用抗生素治疗，阿奇霉素和红霉素更是首选[1-2]。本研究对本院2011年11月～2013年3月收治的80例小儿支原体肺炎患儿分别采用阿奇霉素和红霉素治疗，并对两种抗生素的应用效果进行了比较，现报道如下。 　　1 资料与方法 　　1. 1 一般资料 　　选取本院收治的80例小儿支原体肺炎患儿，入院后对其进行常规检查，确定所选患儿符合《实用儿科学》中关于支原体肺炎的相关诊断标准[3]，排除由病毒及细菌感染引起的肺炎患儿，所有患儿均有不同程度的发热