黄连温胆汤联合西药治疗2型糖尿病合并心绞痛65例临床观察.docVIP

黄连温胆汤联合西药治疗2型糖尿病合并心绞痛65例临床观察 　　【摘要】目的 观察黄连温胆汤联合西药治疗2型糖尿病合并（气虚痰瘀互阻型）心绞痛患者的疗效。 　　方法 选取2015年10月～2016年3月于本院就诊的2型糖尿病合并（气虚痰瘀互阻型）心绞痛门诊患者65例作为研究对象，将其随机分为对照组33例和治疗组32例，观察两组患者治疗前后血糖及糖化血红蛋白水平、心绞痛临床症状积分、心电图及用药不良反应情况。结果 经治疗后，治疗组总有效率为87.5%（显效13例，有效15例，无效4例）；对照组总有效率为63.7%（显效9例，有效12例，无效12例），治疗组疗效显著优于对照组（P0.05）；治疗组治疗后患者血糖及糖化血红蛋白水平、心绞痛临床症状积分、心电图明显改善，且明显优于对照组，差异有统计学意义（P0.05）。此外，本研究未发生药物不良反应或意外事件。结论 黄连温胆汤联合西药可改善2型糖尿病合并（气虚痰瘀互阻型）心绞痛患者的临床症状，控制患者病情发展，明显提高疗效。 　　【关键词】2型糖尿病合并心绞痛；黄连温胆汤；心电图；中医药治疗 　　【中图分类号】R587.1 【文献标识码】B 【文章编号】ISSN.2095-6681.2016.30..03 　　【Abstract】Objective This study aimed to explore the clinical effectiveness of combination of Huanglian Wendan Decoction and western medicine in the treatment of diabetes complicated by coronary disease.Methods Total 65 patients were randomly assigned to control group and treated group， and the blood glucose， glycosylated hemoglobin， score of clinical signs， electrocardiogram， and adverse reaction for these two group were also observed.Results After treatment， the total effective rate of control group was 63.7% （9 excellent patients，12 valid patients， 12 invalid patients）， the total effective rate of treated group was 87.5% （13 excellent patients， 15 valid patients， 4 invalid patients）， which indicated that the efficacy of treated group was higher than control group （P0.05）.The blood glucose，glycosylated hemoglobin，score of clinical signs，electrocardiogram were significant improved in the treated group，and the effectiveness of treated group was higher than control group （P0.05）.In addition， there were no adverse reaction were noted during the course of the study.Conclusion Administration of Huanglian Wendan Decoction and western medicine could improve significantly the clinical signs of diabetes complicated by coronary disease patients and notably enhance the clinical effectiveness. 　　【Key words】Diabetes complicated by coronary disease；Huanglian Wendan Decoction； Electrocardiogram； TCM therapy 　　2型糖尿病是继心脑血管/癌症之后第三大严重危害人类健康的疾病。冠心病心绞痛是其并发