青春期多囊卵巢综合征中医痰湿证素和脂代谢相关性研究.docVIP

青春期多囊卵巢综合征中医痰湿证素和脂代谢相关性研究 　　[摘要] 目的 分析青春期多囊卵巢?C合征（PCOS）中医痰证素、湿证素与脂代谢相关性。 方法 选择本院就诊13～20岁确诊为PCOS的患者165例为研究对象，采用证素辨证和积分的方法，提取痰证素、湿证素，探讨各级痰证素、湿证素积分与总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）的相关性。 结果 在青春期PCOS患者痰证素中，各级别间TC、TG比较，差异均有统计学意义（P0.05）；0级与1级、1级与2级、2级与3级间LDL-C比较，差异无统计学意义（P0.05），其他各级间比较差异均有统计学意义（P0.05）；0级与各级间LDL-C比较差异均有统计学意义（P0.05）。痰证素积分与TC呈高度正相关（r=0.844，P0.01）；与TG呈正相关（r=0.733，P0.01），与HDL-C相关性极弱（r=0.231，P0.01），与LDL-C相关性较弱（r=0.351，P0.01）。湿证素积分与TC呈高度正相关（r=0.827，P0.01）；与TG呈正相关（r=0.665，P0.01），与HDL-C相关性极弱（r=0.260，P0.01），与LDL-C相关性较弱（r=0.338，P0.01）。 结论 中医证素痰、湿是青春期PCOS患者重要的病理因素，脂代谢中总胆固醇及甘油三酯与痰、湿证素关系密切，且随证素积分的升高而升高。 　　[关键词] 青春期多囊卵巢综合征；痰证素；湿证素；脂代谢 　　[中图分类号] R271.9 [文献标识码] B [文章编号] 1673-9701（2016）33-0132-04 　　[Abstract] Objective To analyze the correlation of traditional Chinese medicine（TCM） phlegm syndrome element and dampness syndrome element with lipid metabolism in adolescent polycystic ovary syndrome （PCOS）. Methods A total of 165 patients aged 13-20 years diagnosed as PCOS in our hospital were selected as subjects. With the method of syndrome element differentiation and scoring， phlegm syndrome element and dampness syndrome element were extracted， The correlation of each grade of phlegm syndrome element and dampness syndrome element scores with total cholesterol， triglyceride， high-density lipoprotein and low-density lipoprotein were explored. Results For phlegm syndrome element in adolescent PCOS patients， there was statistically significant difference in total cholesterol and triglyceride among different grades （P0.05）； there was no difference in low-density lipoprotein between grade 0 and grade 1， grade 1 and grade 2， grade 2 and grade 3（P0.05）， there was statistically significant difference in other grades（P0.05）； there was statistically significant difference in low-density lipoprotein between grade 0 and other grades（P 　　[Key words] Adolescent polycystic ovary syndrome； Phlegm syndrome element； Dampness syndrome element； Lipid metabolism 　　多囊卵巢综合