侧链含伯胺基的分子刷型水溶性共轭聚合物的合成、表征与应用-高分子化学与物理专业论文.docxVIP

II II Abstract The brush-type conjugated poymer, which has prima amine and clear structure, has excellent water-solubility and steady fluorescence property. And it can also provide a good modifiability for further study , especially for target modification. But the active hydrogen of prima amine seriously affects the application of related monomer for active controlled radical polymerization. The brush-type conjugated polymer containing prima amine in this paper was synthesized by Atom Transfer Radical Polymerization （ ATRP ） and Reversible Addition-Fragmentation Chain Transfer Polymerization（RAFT）. The research of this paper is forced on three aspect：One is synthesizing the brush-type water-soluble conjugated polymer with the side chain containing prima amine by Atom Transfer Radical Polymerization（ATRP） and Reversible Addition-Fragmentation Chain Transfer Polymerization (RAFT). The second work is charactering the structure of product and testing the photophysical properties of the water-soluble conjugated polymer. The third work is exploring the potential application for detecting metal ion and cell imaging of the water-soluble conjugated polymer. The macromolecular ATRP initiator and RAFT agent is synthesized for ATRP and RAFT. Firstly , 2,7-dibromo-9,9 - di (3 - hydroxypropyl)-fluorene and 9,9 - dioctyl fluorene-2 - boric acidester is synthesized from 2,7 - dibromo-fluorene. And then, the polyfluorene with the side chain containting hydroxyl group is synthesized by Suzuki coupling reaction. The macromolecular initiator of ATRP and macromolecular chain transfer agent of RAFT are synthesized by introducing ATRP initiator and RAFT agent to the side chain of polyfluorene. The polymer PF-PGMA and PFNH-Boc are synthesized from monomer GMA and N-Boc-ethylamine methacrylate through atom transfer radical polymerization(ATRP). The polymer PF-PGMA-NH2 is synthesized by dealing with the product which was achieved by opening the ring of PF-PGMA. The polymer PFNH2 is achi