甲氨蝶呤联合垂体后叶素在腹腔镜输卵管妊娠切开取胚术中的应用分析布.docVIP

甲氨蝶呤联合垂体后叶素在腹腔镜输卵管妊娠切开取胚术中的应用分析布 　　【摘要】 目的：探讨甲氨蝶呤（MTX）联合垂体后叶素在腹腔镜输卵管妊娠切开取胚术的临床效果。方法：选取2011年6月-2013年12月行腹腔镜输卵管妊娠切开取胚术患者128例，将其随机分为试验组66例及对照组62例，试验组局部注射垂体后叶素联合MTX，对照组则不用药，比较两组术中的出血量、手术时间、血β-hCG降至正常时间、持续性异位妊娠发生率及输卵管通畅程度。结果：试验组术中出血量、手术时间、术后β-hCG值降至正常的时间及术后持续性异位妊娠率均少于对照组，两组比较差异均有统计学意义（P0.01）。试验组行子宫输卵管造影显示通畅60例，不通畅6例；对照组通畅51例，不通畅11例，两组比较差异有统计学意义（P0.05）。结论：使用垂体后叶素联合MTX局部注射既保护患者的输卵管，减少了手术出血及手术时间，更重要的是减少了持续性异位妊娠的发生，对再次妊娠也有益处。是一种安全、简便、可靠有效的方法，具有较高的临床价值。 　　【关键词】 垂体后叶素； 甲氨蝶呤； 腹腔镜； 输卵管妊娠 　　中图分类号 R713.8 文献标识码 A 文章编号 1674-6805（2015）3-0001-03 　　The Clinical Analysis of Methotrexate Combined with Pituitrin in Embryo Removal by Laparoscopic Salpingotomy for Tubal Pregnancy/BU Zhan-hong，XIONG Xiao-qin.//Chinese and Foreign Medical Research，2015，13（3）：1-3 　　【Abstract】 Objective：To study the clinical effect of Methotrexate（MTX） combined with Pituitrin in embryo removal by laparoscopic salpingotomy for tubal pregnancy.Method：128 cases embryo removal by laparoscopic salpingotomy for tubal pregnancy from June 2011 to December 2013 were selected.They were randomly divided into the experimental group for 66 cases and the control group for 62 cases，the experimental group was injected MTX and Pituitrin，the control group was no drugs，two groups of perioperative blood loss，operative time，blood in beta hCG dropped to normal time，the incidence of persistent ectopic pregnancy，and degree of fallopian tube patency were compared.Result：The intraoperative blood loss，operative time，postoperative beta hCG value dropped to normal time and postoperative persistent ectopic pregnancy rate in the experimental group were less than those of the control group，the differences were statistically significant（P0.01）.The experimental group uterus oviduct imaging showed unobstructed 60 cases，not unobstructed 6 cases；the control group flow 51 cases，not unobstructed in 11 cases，there was statistically significant（P0.05）.Conclusion：The use of Pituitrin combined MTX local injection in patients with tubal，both to red