我院门诊抗菌药物处方剖析.docVIP

我院门诊抗菌药物处方剖析 　　[摘要]目的 对我院门诊抗菌药物使用情况进行分析，评价其合理性，为抗菌素使用提供指导。方法 从本院2015年4月1日～10月31日279 174张门诊处方筛选出抗菌药物处方有28 294张，统计本院抗菌素使用的具体情况，依据《抗菌药物临床应用指导原则》，分析本院抗菌素使用是否规范合理。结果 本院调查的门诊处方总共279 174张，含抗菌素处方达10.13%，有抗菌素处方28 294张，使用频次达29 378次，其中包括口服的抗菌素54.11%，注射用抗菌药物39.06%，头孢菌素类43.15%，大环内酯类也占18.34%；抗菌素不合理使用的处方仅仅只达抗菌素总处方数0.456%，只有129张，使用抗菌素不合理的主要包括溶媒的选用不符合使用的原则、抗菌素使用的方法和用量未达要求以及联合使用抗生素的方法不对等。结论 本院门诊使用的抗菌药物的总体合理性高，只存在极少数使用的情况是不合理的，然而患者以性命相托，为保证其的健康生活，我院仍需加大力度保证安全合理用药并及时反应不足之处，以共借鉴。 　　[关键词]门诊处方；抗菌药物；分析；合理使用 　　[中图分类号] R978.2+4 [文献标识码] A [文章编号] 1674-4721（2016）07（c）-0109-04 　　[Abstract]Objective To analyse the usage of antibacterial drugs in our hospital outpatient clinicand to evaluate its rationality，to provide guidance for antibiotics.Methods 279 174 sheets ofoutpatient prescriptions in our hospital from April 2015 to October were selected，including 28 294 prescriptions for antimicrobial agents，to count the use of antibiotics in our hospital outpatientand to analyze the rationality of using antibioticsaccording to Guidelines for Dlinical Application of Antimicrobial Agents.Results 279 174 sheets of prescription was collected，in which 28 294 antimicrobial prescription was accounted for 10.13%；The frequency of use of antimicrobial agents was 29 378 times，oral antibiotics accounted for 54.11% and antimicrobial agents for injection accounted for 39.06%；The use ofcephalosporin was accounted for 43.15% and the use ofmacrocyclic lactone was accounted for 18.34%；129 sheets of prescriptions for improper use of antibioticswasaccounted for 0.439% of allprescriptions for antimicrobial agents，including inappropriate usage and dosage，no suitable solvent and inappropriate combination therapy.Conclusion The use of antimicrobial agents in our hospital has a very small number of unreasonable，it is reasonable in general.In order to patients′ life and health，it is necessary to increase efforts to ensure the safety and rational use of antimicrobial agents and timely response deficiencies. 　　[Key words]Ou