磁敏感加权成像及波谱成像在脑星形细胞瘤分级诊断中的价值分析-影像医学与核医学专业论文.docxVIP

8 8 Sensitivity and specificity in ROC analyses.There were the threshold of 2.54 and AUC of 0.858 for Cho/NAA of the core of tumor to provide sensitivity 85.0%、specificity 83.0% and accuracy 84% to differentiate the high-grade astrocytoma; Likewise,there were the threshold of 2.56 and AUC of 0.794 for Cho/Cr to provide sensitivity 54.0% 、specificity 92.0% and accuracy 78% .The threshold of 0.51 and AUC of 0.651for NAA/Cr to provide sensitivity 54.0%、specificity 79.0% and accuracy 70%. It was Significant different in statistics that the Cho/NAA, Cho/Cr and NAA /Cr determined high-grade astrocytoma respectively（p0.05）.④ Sensitivity and specificity for the C value and combination of Cho/NAA was 100% and 83.3%. Conclusion: ① SWI could increase the specificity and the metabolite ratios of MRS could increase accuracy in grading astrocytoma to comparing with routine MRI imaging. ② It could increase the sensitivity in grading astrocytoma to combine the C value with the Cho/NAA. Key words: Magnetic resonance spectroscopy (MRS); Susceptibility weighted imaging(SWI); Astrocytoma;Receiver operating characteristic(ROC) PAGE PAGE 3 英文缩略词表 英文缩写 英文全称 中文全称 SWI MRS AUC CT FOV MRII NEX ROI T1WI T2WI SNR TE TR ROC 曲线 Cho Cr NAA VOI TSE GRE EPI FIR TI ETL ES susceptibility weighted imaging magnetic resonance spectroscopy area under curve computed tomography field of view magnetic resonance imaging number of excitation Region of interest T1-weighted image T2-weighted image signal noise ratio echo time repetition time Receive operating charateristic curve Choline creatine N-acetyl asparte voxel of interest turbo spin echo Gradient recalled echo echo plannar imaging fast inversion recovery time inversion echo train length echospacing 磁敏感加权成像 磁共振波谱成像 曲线下面积 计算机体层成像 视野 磁共振成像 激励次数 感兴趣区 T1 加权像 T2 加权像 信噪比 回波时间 重复时间 受试者工作