葛根芩连汤对溃疡性结肠炎大鼠作用机制的研究-方剂学专业论文.docxVIP

to detect rats in colon tissue MTL, VIP expression; By ELISA determination colon tissue P choose meat level; Rats were observed under tem colon tissue ultrastructural changes. Results: GeGenQin even dismantling welling-abscess and part of the group to diagnose ulcerative colitis rats in colon tissue MTL, VIP impact: and group A (normal group) comparison, group B, C group, D group, group E, F group, the group G, H experiment in rats and VIP MTL colon tissue were significantly higher levels of A group; And the group B (model group) comparison, group C, D group, the group E, F group, the group G, H experiment in rats and VIP MTL colon tissue significantly reduced (the content of group C P0.01, group D P0.05, P0.05), and the group E F P0.05, group G P0.01, group H P0.01,). GeGenQin even dismantling welling-abscess and part of the group to diagnose ulcerative colitis rats in colon organization offering the influence of choice P level with group A (normal: A comparison group), group B, C group, D group, group E, F group, the group G, H experiment in rat colon tissue vegetarian level choice P were significantly higher than A group; And the group B (model group) comparison, group C, D group, the group E, F group, the group G, H experiment in colon tissue rats were vegetarian level choice P is significantly reduced (group C P0.01, group D P0.05, P0.05), and the group E F P0.05, group G P0.01, group H P0.01,). Were observed under tem each rat colon tissue ultrastructure compared with the rest of the group A, among which are change each group C, G group, obviously, group H change group D, E group, change is obvious group F. Conclusion: The party of gegenqinlian decoction to dismantle and part of rats UC qi-deficiency colon tissue MTL, VIP, P choose meat and colonic mucosal ultrastructure caused the most effect medicine group is the puerarin, rhizoma coptidis, roasted liquorice combination. Of gegenqinlian decoction mechanism of action may be UC gegenqinlian decoction has reduc