鼻咽癌调强适形放疗对甲状腺血流动力学改变与功能影响的前瞻性分析.pdfVIP

贵阳医学院2011 级硕士研究生论文 Follow-up time of 3 months to 12 months, the median follow-up time was 5.5 months. 1. 100 patients with 3-month follow-up. (1)hypothyroidism: the end of radiotherapy immediately subclinical hypothyroidism two cases , hypothyroidism incidence of 2%; 3 months after radiotherapy, 7 cases of subclinical hypothyroidism occurred, 8 cases of clinical hypothyroidism, in which 2 cases transform from subclinical hypothyroidism into clinical hypothyroidism, the incidence of hypothyroidism is 15%. Of 8 hypothyroidism cases, 2 cases displayed fatigue, cold symptoms, 1 case displayed dry skin, and the rest does not show clinical manifestations of hypothyroidism. 3 (2) Thyroid volume changes were: 13.86±3.41cm3, 13.84± 3.37cm , 3 12.70±3.67cm before radiotherapy, after the end of radiotherapy and three months . Compared with before radiotherapy, there was no significant difference (P0.05) of volume change before the end of radiotherapy immediately, 3 months after radiotherapy volume was statistically significant difference (P0.05). (3) The changes of thyroid hormone after radiotherapy prior to radiotherapy, radiotherapy end immediately ,3 months: the level of FT3 were 4.98 ± 0.61pmol/L, 4.92 ± 2.79pmol/L, 4.39 ± 0.87pmol/L, the level of FT4 was 15.77 ± 2.58pmol/L, 15.74 ± 4.62pmol/L, 14.56 ± 2.33pmol/L, the level of TSH was 1.69 ± 0.89mIU/L, 1.75±1.19mIU/L, 3.03 ±2.76mIU/L. The levels of FT3, FT4 began to drop at the end of radiotherapy, but the level of TSH el