降糖一号干预代谢综合征的临床研究-中医内科学专业论文.docxVIP

中文摘要中文接要 中文摘要 中文接要 我谢综合痉怒由胰繇素抵挠为核心的一系列代谢异常，包括释髀，高盘压， 囊脂冥常，糖藜量异寤等，撩霖上鸯报高静发病辜，被广泛藿辚。本课鼷蔫重 予默岛索羝按的中医药滚疗戆磺究，全殛收集了反映中医各派各家学术鼹淼躲 文欺资料，进行整理瓤归纳，总结概括出脬胃共治的作慰梗理秘涯浓糕律。同 时通过临床观察初步探讨了蹲糖一号对胰岛素敏感性、体重、虫赡、胰避豢分 泌时相的影响。 本课题是基于导师长期的临床实践观察，即多数代谓{综合癌患案发病前有 一个过食、体型偏胖的阶段，发病早中期多伴有烦躁易怒、胸胁胀满、多食易 饥、小便黄赤、口干口苦、大便干燥、舌红苔黄、脉弦数或滑实有力等症，中 医辨证为肝胃郁熟。导师以此立法，治以疏肝泻热和胃，化瘀通络，在《伤寒 论》大柒胡汤和《伤寒论》抵挡汤的基础上创立了降糖一号。本课题以文迪雅 为阳性对照组，躐察了57佣代湔综台症患者治疗前后体重及腰围、腹围、臀 囤、盘糖、胰岛素、胰岛素敏感指数、血貉、症状积分等指标的变化。结采表 赣，降糖一号辩代谢练合瘟患者静盘糖、盘膳紊乱存明显的改善作沼，并能减 轻体重、撼离患者抟胰岛索敏感往、改蓉；玉矮易怒、鹃胁胀满，大便予澡等箍 寐痰状。 降糖一号治疗代谢综合瘗鸵机制增霹能与减照，减少凝黢基，改善斑黯紊熬， 增加胰岛索的敏感性等有关，其具体终用机制还鸯德逃一步撵讨。 童聪词： 代谢综合征 胰岛素抵抗 降糖一号 中医药治疗 4 4 降耱一号手预谯澈综合薤鹃疆瘃研究 ABSTRACT Metabolic syndrome is a series of metabolic abnormity whose core is insulin resistance，including obesity，hypertension，blood-fat abnormity，sugar tolerance abnormity．This disease has high incidence and been thought highly in clinic．This topic put importance on TCM research of insulin resistance，arranging and inducing different TCM learning standpoint，summing up the action mechanism and treatment regularity of treating on liver and stomach．We investigate that jia珏gta撞gyihao affect the insulin sensibility， weight， blood fat and insulin secretion phrase on clinic initially。 This topic is on account of my advisor’S long-term practical observation in clinical．We find that most patients of metabolic syndrome have hyperphagia and fat stage before they have MS。They often have restlessness and tantrum，fullness in chest and hypochondrium，polyphagia and hungry，yellowish or reddish urine， dry mouth，bitter taste of mouth，dry stool，red tongue with yellowish fur，string and frequent slide pulse in the early metaphase．The differentiation of symptoms and signs of TCM is hepar—gastric heat retention．Then we treat it from dispersing the depressed liver—energy，regulating the stomach，ducing the heat． dispersing b