风毛菊中木脂素苷结构确定和碳化学位移的取代位移效应规律.PDF

·772· 　Chine e T raditio nal and Herbal Drug 　2002 33 9 ·· 师彦平,马　骥 ( , 　730000) 　: 　 Saussurea j ap on ica ,。 　 HPL C、,( N M R)( M S); (Ⅰ ,Ⅱ ,Ⅳ ,Ⅴ ,Ⅶ ,Ⅹ ), C-1 ,()。 　 ( 75% ) 3,: (+ ) -1-hy drox y pinore inol-4″-β-D -glu- (Ⅵ ) , (+ ) - -4- - - (Ⅷ ) ( + ) -1- -4′- - - copyr ano ide laricir e inol β D glucopy rano ide laricir e inol β D glucopy rano ide (Ⅸ ) ; C-1 [Δδ= δ () - δ ()= - 4. 2] , C1′ C1′ = 3. 0。　Ⅵ ,Ⅷ Δδ Ⅸ ;, , 。 : ;; : 284. 1　　　: 　　　: 0253 2670( 2002) 09 0772 04 R A Lignan glycosides fromSaussurea j ap onica and rules for substituted effects 13 (+ )- (+ )- on CNMR chemical shifts of pinoresinol and lariciresinol - , SHI Yan ping M A Ji ( Northw e t R D Center of N atur al Drug , Lanzhou In titute of Chemical Phy ic , Chine e Academy of Science , Lanzhou 730000, China) Abstract: Object　 To i olate and identify the chemical con tituent of S aussurea j ap on ica ( Thunb. ) DC. and to obtain ome rule of chemical hift eff ect o n hydroxy latio n and O-glyco y latio n. Methods　 The con tituent w ere i olated by ilica g el column chromatography and HPLC ( RP-18) , and their truc- ture w ere elucidated through pectro copic analy i ( N M R and FABM S) . The rule w ere obtained by com pari o n w ith tho e of know n analo gou lignan . Results　 Three lignan glyco ide w ere i olated and identified a (+