超重患者髓核组织中TNF-α、IL-1β的表达与其与疼痛的相关性.pdfVIP

l 1 e3lFN—f00t～州一Q、14．Q、IL·-113inthe T’pressionsexpresslons nucleus of pulposus and overweightpatientspain ABSTRACT ective：Itis believedthattumor Obj necrosis factor仪(TNF．曲， the twokindsof interleukin-1／3(IL-1回are important inthe immunoreactionandinflammationcoursein participate kindsof many diseases aimedat the rsepectively．We investigatingexpressionTNF—or,IL．1口 in nucleus in LDH and the pulposus overweightpatients studyingrelationship betweenthe two andthe of parameters degreepain． with Methods：Thirtymedical and patients history,clinicallyaccessory and LDHwere examinations(X—ray,CT of MRI)determined studied．Twenty themwere ofthem were non。overweight(BMI24)，ten had nodifferencein anddisease 24)．砧lgroups