活血通管汤与丹参注射液治疗输卵管阻塞的临床研究-中医妇科学专业论文.docxVIP

提要 提要 砭465055 -- 目的：探讨活血通管汤内服配合丹参注射液官腔注射治疗血瘀型输卵管 阻塞的治疗机理。 方法：82例输卵管阻塞患者(血瘀型)随机分为中药组(50例，活血通管汤 内服配合丹参注射液宫腔注射)及西药组(32例，仅用庆大霉素注射液加生理 盐水通液)，观察治疗前后临床症状的改善，血液流变学，卵巢动脉血流动力学 等参数的变化及输卵管通畅度的改善。 结果：患者存在血液流变学和卵巢动脉血流动力学的异常，表现为全血粘 度、纤维蛋白原、搏动指数、阻力指数的升高。治疗前两组在临床症状、血流 变、卵巢动脉血流动力学方面无显著性差异(P0．05)，治疗后，中药组在降低 全血粘度、纤维蛋白原、搏动指数、阻力指数方面显著优于西药组(P0．05)。 中药组在输卵管复通率、妊娠率、改善症状方面也显著优于西药组(PO．05)。 结论：活血通管汤内服配合丹参注射液官腔注射是治疗血瘀型输卵管阻 塞的有效方法和方药，能通过多个环节提高输卵管再通率，促进受孕。 关键词：输卵管阻塞血流变卵巢动脉血流动力学活血通管汤 丹参注射液 ，·严咖s呻帆T。咖嘶西㈣嘣葩Oviduct ，·严咖s呻帆T。咖嘶西㈣嘣葩 Oviduct by Huo Xue Tong Guan Decoction and Dan Shen injection Speciality：Gynecology of TCM，the Stuay on Female Infertility Tutor：Professor Wu Xing Huo Student：Li Xing Zheng Objective：To explore the mechanism of treating obstructed oviduct by Huo Xue Tong Guan Decoction and Dan Shen Injection(HXTGD+DSI)．Metlmds：82 Patients were divided randomly into the TCM group(50 cases treated with HXTGD+DSl)and the control group(32 cases treated with gentamycin)．Two gToups were compared from aU the following aspects：the improvements ofclinical symptoms，the bloodrheology，the ovarian bemodynamics，the ovarian recanalization rate and the pregnant outcome．Re— sults：Patients were associated with the abnormal of blood theology and ovarian hemody— namlcs：elevated blood viscosity。fibrinogen，PI and m．There Was no significant differ- ence in elinical symptoms and ovaxi∞hemodynamics indexs before treatment between the two groups．After treatment，there_qas significance in reducing blood viscosity，fib- rinogen，PI and RI between two greups(P0．05)．Moreover，the TCM group has sig— nificance in reliefimg clinical symptoms．enhancing ovarian Hx坦Ilali刎on rate and preg- nant rate(P0．05)． Conclusions：HXTGD+DSI could nx甚nalize the obstruction of fallopian tube with blood stasis syndrome，improve the clinical symptoms and enhance pregnant rate multy—ettlctively． Key Words：Obstmction of oviduct／Blood Rheology／Ovarian hemodynamlcs／ Huo Xue Tong Guan Decoction／Dan Shen Injection 引 引 言 输卵管阻塞性不孕占整个女性