甲钴胺治疗突发性耳聋的疗效研究-耳鼻咽喉头颈外科专业论文.docxVIP

Curative Curative effect of Methylcobolaninc on sudden deafness Abstract Objective To evaluate the curative effect of methylcobolaninc on sudden deafness．Methods 137 cases(141ears)were divided into 3 groups．I group 66cases(69ears)were treated with methylcobolaninc， II group 46 cases(46ears)were treated with the caleium eharmels blocker，III group 25 cases(26ears)were treated with betahistine．A1l groups were treated with vasodilating medicines．Result①The effective rates of treatment in the three groups were 65．2％，71．7％，57．6％respectively,and the cure—obvious rates in 4kHz-8kHz portion oftreatment were 34．9％，21．4％，13．3％，either 2 difference of x test was not significant(P0．05)．②The effective rates of deducing the tinnitus were 76．5％，73．7％，73．9％and the difference was not significant．(勖The effective rates ofcontrolling vertigo were 82．6％，61．9％， 85．7，the difference was not significant，but the difference of the disappearance rate was significant(P0．05)．Conclusion①The difference of the curative effect was not significant in the three groups of SD patients． Methy’lcobolaninc and medicines of improving inner ear microcirculation should be used in combination to achieve better curative effect．@)Although In I group the differences were not significant．the effective rates of treament in 4kHz～8kHz portion and the effective rate of deducing the tinnitus were better than the other two groups．The disappearance rate of controlling vertigo was obvious．⑨The effective rate of calcium channels blocker Was stable，the effective rate of betshisine in treatment of vertigo WaS more obvious． Key word：sudden deafness methylcobolaninc calcium channels blocker betahistine curative effect 甲钴胺治疗突发性耳聋的疗效分析摘 甲钴胺治疗突发性耳聋的疗效分析 摘 要 目的观察甲钴胺治疗突发性耳聋(sD)的疗效。方法 137例141耳 分为三组，I组66例69耳用甲钴胺治疗为主，II组46例46耳用钙离子 拮抗剂治疗为主，III组25例26耳用盐酸倍他司汀(BH)治疗为主，三组基 础用药均为扩血管剂。陆果 ①三组听力改善的有效率分别为65．2％， 71．7％，57．6％，对4KHzL8KHz高频段痊愈+显效率分别为34．9％，21．4％， 13．3％，二组x 2检验差异均不显著(PO．05)。⑦三组改善耳鸣疗效分别为 76．5％，73．7％，73．9％，差异不显著。③三组改善眩晕疗效分别为82．6％， 61