散瞳饮水暗室低头激发试验在可疑青光眼中的临床应用-眼科学专业论文.docxVIP

·中文结构式摘要·散瞳饮水暗室低头激发试验在可疑青光眼 ·中文结构式摘要· 散瞳饮水暗室低头激发试验在可疑青光眼 中的临床应用 目 的 观察并评价散瞳饮水暗室低头激发试验(Mydriasis water-drinking dark—room lower-head．position provocative test，MWDLPT，PT)在可疑青光眼(Glaucoma suspects，GS)中的临床应用。 方 法 收集2004年2月-2010年1月间于中国医大一院眼科门诊青光眼组就诊的GS 共37例(74H[曼)，年龄15～78岁(平均年龄50．7±19．3岁)。非同日分别行PT和日 间眼压(Daytime intraocular pressure，DIOP)测量等辅助检查，分别记录两种方 法测得的眼压波动值(AIOP)和眼压峰值(Peak lOP)，两种方法均以AIOP≥ 8mmHg为阳性，比较两种方法参数间的关系。分别比较P，r结果与周边前房深度 (Peripheral anterior chamber depth，PACD)和年龄(Age)间的关系。采用r检 验及线性回归分析进行统计学分析，以P0．05表示有统计学意义。 结 果 PT阳性者为21例(37f11曼)。无1例出现严重的并发症(如明显的眼痛，头痛，视 力下降及恶心呕吐等)。所有PT试验对象的眼压在试验后1-2d,时内降至基线水 平，部分病例应用了缩瞳剂。PT与DIOP两种方法的Peak lOP成显著的正相关关 系，且PT法的阳性率显著高于DIOP法。在PACD≤1／4角膜厚度(Corneal thickness，CT)组PT的阳性率显著高于PACD1／4CT组。PT法AIOP与年龄无 相关性。 结 结 论 PT可作为一种新的可疑青光眼的激发试验，在对眼压波动情况的检查上优于 DIOP法，可能更适用于闭角型青光眼(Angle—closure glaucoma，ACG)，且不受 年龄影响，应用范围较广泛，是一种相对安全有效的检查方法。 关键词 激发试验；可疑青光眼；日间眼压 2 ·英文结构式摘要·The ·英文结构式摘要· The Clinical Application of Mydriasis Water-drinking Dark-room Lower-head——position Provocative Test in Glaucoma Suspects obj ective To investigate and value the clinical application of the myariasis water-drinking dark-room lower-head-position provocative test(MWDLPT,PT)in glaucoma suspects (GS)． Methods Medical records were reviewed of 74 eyes in 37 patients who were diagnosed wim GS at Glaucoma Clinic in the First Hospital of China Medical University from February 2004 to January 20 1 0．The age ranged from 1 5 to 78 years，and the average age was 50．7a：19．3(mean--LSD)years．All the individuals received PT and daytime intraocular pressure(DIOP)measurement on different days．The fluctuation of intraocular pressure(AIOP)induced by PT and recorded by DIOP measurement were obtained and compared．An increase in lOP of at least 8mmHg from baseline Was considered a positive result for both of the two methods．Statistical analysises were performed by Chi-square test and linear regression analysis to assess the distinction of the results between different methods and between different p