慢性假性肠梗阻110例临床治疗分析.docVIP

［ ］目的探讨慢性假性肠梗阻的最佳临床 治疗方法。方法对1995年6月~2011年1月在我院 治疗的110例严重慢性假性肠梗阻患者进行回顾性分 析，将其分为手术组（62例）和非手术组（48例）。 手术组行盲肠造痿、病变肠管切除手术，非手术组行 保守治疗。通过对生存率、疾病复发、术后并发症和 生活质量的分析来比较手术治疗与非手术治疗的治疗 效果。结果手术组患者预后在生存率、疾病复发及 生活质量方面明显优于非手术组（RR死亡=0.49, P=0.020.05； RR 复发=0.46, P=0.000 K0.01； RR 生 活质量=0.52, P=0.000 10.01）o两组在并发感染方面 比较，差异无统计学意义（RR并发感染=1.06, P=0.80 0.05）o结论手术治疗严重慢性假性肠梗阻能有效 改善患者预后。 ［关键词］假性肠梗阻；手术；预后 ［ ］R574.2 ［ ］B ［ ］ 1673-7210 （2011） 12 （a） -190-02 Analysis on clinical treatment of 110 patients with chronic intestinal pseudoobstruction SHI Jinsong Department of General Surgery, the Center Hospital of Yiyang City, HiTnan Province, Yiyang 413000, China [Abstract] Objective: To study the best clinical treatment method of chronic intestinal pseudoobstruction (CIP). Methods: A retrospective study of 110 patients with serious CIP in our hospital from June 1995 to January 2011 was analysed? 110 patients were divided into surgery group (62 cases) and non-surgery group (48 cases)? Surgery group were given surgical treatment such as colostomy and cutting lesion intestines. The data on death, recurrenee, postoperative complications and quality of life of two groups were analyzed to compare the surgery and non-surgery methods? Results: The survival rate, disease recurrenee, postoperative complication and quality of life of the surgery group were better than that of non-surgery group (RRdeath=0.49, P=0.020.05; RRrecurrence=0.46, P=0.000 K0.01; RRquality of life=0.52, P二0.000 1 0.01). There was no sign ifica nt d iff ere nee betwee n surgery group and non-surgery group in terms of complicated infection (RRinfectious diseases=1.06, P=0.800.05). Conclusion: Surgical treatment may be a good choice to improve the pro gnosis of patie nts with serious chronic intestinal pseudoobstruction. [Key words] Intestinal pseudoobstruction; Surgery; Pro gnosis 慢性假性肠梗阻(chronic intestinal pseudo-obstruction, CIP)是一种没有机械性梗阻因素 但具有肠梗阻症状，以胃肠道缺乏协调运输功能为特 征的临床综合征⑴。慢性假性肠梗阻可分为原发性和 继发性两类，原发性是由肠道平滑肌异常或肠神经系 统异常造成，而继发性病因主要有结缔组织病、内分