急性脑血栓应用皮下注射低分子肝素钙联合奥扎格雷钠治疗的效果分析.docVIP

急性脑血栓应用皮下注射低分子肝素钙联合奥扎格雷钠治疗的效果分析 颜建辉黄丽娟罗高梅王文婷 (湘南学院临床系/湘南学院附属医院综合内科湖南郴州423043) (湘南学院附属医院康复科湖南郴州423043) (湘南学院附属医院综合内科 湖南 郴州423043) 摘 要 目的对应用皮下注射低分子肝素钙联合奥扎格雷钠治疗急性脑 血栓的临床疗效进行分析探讨。方法回顾性分析我院2013年5月?2014年12 月期间收治的92例急性脑血栓患者资料，按照患者入院先后顺序将其设定为研 究组46例与对照组46例。两组患者均进行常规抗感染、改善微循环、维持水电 角质平衡等基础治疗，对照组在此基础上给予单药奥扎格雷钠进行治疗，观察组 应用皮下注射低分子肝素钙联合奥扎格雷钠治疗进行治疗，在连续给药两周后, 对两组患者临床疗效进行对比分析。结果治疗组患者基本治愈27例，显著进 步9例，进步6例，治疗总有效率为91.3%；对照组基本治愈20例，显著进步7 例，进步8例，治疗总有效率为76.1%,两组患者疗效比较，差异有统计学意义 (P 0.05)。治疗两周后与治疗前比较，治疗组患者治疗后神经功能缺损评分为 (5?23plusmn;2.17)分,明显优于治疗前评分(21.25plusmn;3.63)分；对照组 治疗后神经功能缺损评分为(8.74plusmn;3.15),明显优于治疗前评分 (21.64plusmn;4.25)分。两组患者治疗前神经功能缺损评分比较差异不存在统 计学意义(P0?05),治疗后神经功能缺损评分相比，治疗组明显优于对照组, 差异存在统计学意义(PV0.05)。结论应用皮下注射低分子肝素钙联合奥扎格 雷钠治疗急性脑血栓的临床疗效显著，能有效改善神经功能缺损评分，且不良反 应少，值得在临床上推广应用。 关键词 急性脑血栓；低分子肝素钙；奥扎格雷钠 (2015) 8-0442-02 [Abstract] Objective: clinical application of subcutaneous injection of low molecular heparin calciumcombined with sodium ozagrel in treatment of acute cerebral infarction were analyzed. Methods: retrospective analysis of 92 cases of acute cerebral thrombosis patient data in our hospital from 2013 May -2014 year in December period, according to the order of admission of the patients will be set as the study group 46 cases and control group of 46 cases. Two groups of patients were carried out with conventionalanti infection, improving microcirculation, maintain hydropower horny balanee of basic treatment, the controlgroup was treated on the basis of single drug Ozagrel treatment, the observation group application of subcutaneous injection of low molecular heparin calcium combined with sodium ozagrel in the treatment for treatment, in continuous two weeks after administration, comparative analysis of two groups of patientsclinical curative effect. Results: the patients in the treatment group were cured in 27 cases, 9 cases of significant progress, progress in 6 cases, the total effective rate was 91.3%; the control group cure 20 cases, 7 cases of sign讦icant progress, progress in 8