中药联合奥施康定治疗60例肺癌患者中重度癌痛的临床分析.docxVIP

中药联合奥施康定治疗60例肺癌患者中重度癌痛的临床分 析 吴玉昌 崇州市屮医医院 四川崇州611230 摘要：冃的 探析痛灵汤联合奥施康定治疗屮重度肺癌癌痛患者的临床疗效 及安全性，为今后有效减轻屮重度肺癌患者疼痛提供新的思路和参考。方法随 机选取肿瘤科收治的120例中重度肺癌患者，采用抽签法将其分为2组，每组 60例，两组患者均给予原发病综合治疗，对照组在此基础上单纯给予奥施康定， 治疗组在对照组用药基础上给予自拟痛灵汤，观察两组患者疼痛、中医症候、生 活质量改善情况以及不良反应发生情况。结果治疗组疼痛缓解率为98.33%明 显高于对照组的88.33% (chi;2二4.8214, P=0.0281),治疗组总有效率为80.00% 明显高于对照组的56.67% (chi;2二7.5481, P二0.0060)；经过2疗程治疗后,两 组患者QOL评分均明显提高(PV0.05),治疗组QOL评分提高程度明显优于对 照组(PV0.05),未发现和治疗相关的不良反应。结论通灵汤联合奥施康定治 疗屮重度肺癌可明显缓解其疼痛程度，改善患者的临床症状和体征，提高其生活 质量，且尚未发现不良反应，故可作为临床治疗癌痛的方案。 关键词：肺癌；中重度癌痛；奥施康定；痛灵汤；疗效；不良反应 Abstract objective of Tong Ling decoction combined with Oxycontin in the treatment of severe cancer pain in patients with lung cancer clinical efficacy and safety of and for future effective alleviate severe pain in patients with lung cancer provide new ideas and ref ere nces.Methods ran domly selected tumor hospital from 120 cases of in patients with lung cancer patients， were randomly divided into 2 groups, 60 cases in each group, two groups of patients were given primary disease comprehensive treatment，the control group based on simple Oxycontin, treatment group in the control of backleg pain Ling decoction treatment group on the basis of observed two groups of patients with pain, TCM symptoms and quality of life improvement and adverse reaction incidence.Results treatment group, the pain remission rate was 98.33%) was significantly higher than that of the control group of 88.33% (x2 2=4.8214 P=0.0281), the treatment group total effectiveness 80.00%) was significantly higher than that of the control group of 56.67% (x2 2=7.5481, P=0.0060)； after 2 courses of treatment, Q.OL scores of the two groups were significantly improved (P lt; 0.05 ), the treatment group QOL scores improved significantly superior to the control group (P lt; 0.05) and not found and treatment related adverse reactions.Conelusion psychic decoction combined with Oxycontin treatment in patients with lung cancer can relieve pain and improve the patients clinical