GRACE危险评分和NT-proBNP水平与急性冠脉综合征患者近期预后的研究.pdfVIP

2 内蒙古医科大学硕士研究生学位论文（2015） CorrelationstudiesofGRACEriskscoreandNT-proBNPlevelwith recentprognosisin patientswithacutecoronarysyndromes Abstract Objective Thepurpose ofthis studywastoinvestigatethe globalregistered acutecoronary events(GRACE) scoreandaminoterminalbrainnatriureticpeptide (NT-proBNP) levelsin patients with acute coronary syndrome (ACS) recent prognosis prediction ability, and their correlation Methods Ourmethodhas covered 160caseswithACS andthepatients’general situations were recorded, including the NT - proBNP in plasma levels on admission, and the patients withGRACEriskscoreevaluationaccordingtotheGRACEscoresforriskstratification(108 low-risk group, or less, 109-140in the intermediate risk category 140high-risk groups), accordingtotheguidelinesforthestandardtreatmentofACS Finally,theirheartbloodvessel of adverse events (MACE) were also recorded after 30 days of their discharge from the hospital,andtheabovedataforstatisticalanalysiswasfinished Results Participants included 160patients, hospital MACE incident rate was 22.5%, the follow-upof30-dayMACEincidentratewas37.5%,afterstatisticsanalysisgetthefollowing results:1By logistic regression analysis found that smoking, age, hyperlipidemia, high GEACE score and high on the NT - proBNP levels are independent risk factors for the developmentofrecentoutcomesforpatientswithACS2.Hospitalpatients,30daysoffollow- up incidence of MACE and GRACE scores were positively correlated (P 0.05) 3NT - proBNP level is significantly higher than patients with MACE events did not happen (P 0.05) Conclusion 1GRACE score,NT -proBNP level, age, smokingandhyperlipidemia arerisk factorsinpatients withACSrecent MACE 2.GRACE scoreandtheNT -proBNP level are independentpredictors ofrisk ofrecent outco