药物警戒与用药安全.pptVIP

药物治疗错误是ADEs的重要因素之一 Medication Errors 是威胁临床用药安全的重要因素 — 美国报道每年因医疗差错(medical error)致死98，000 例 （Committee on Quality of Health Care in America， National Academy Press, 1999. P 233）— 医疗差错中的 20 %与用药错误有关。 （Thomas E J et al. Incidence and types of preventable adverse events in elderly patients: Population based review of medical records. BMJ 2000; 320 : 741 ） 23 第三十页，共78页。 药物治疗错误的危害 每100例非产科住院患者中发生6.5 次 ADEs ADEs 中28 % 是可预防的。 致命性的、严重ADEs中，42 %是可预防的 每例可预防的ADEs, 导致住院时间延长4.6天 受调研单位因ADEs导致医药费增加达$ 560万元 — Bates DW et al: The costs of adverse drug events  in hospitalized patients. JAMA 1997 277: 307 24 第三十一页，共78页。 药 物 治 疗 错 误 的 危 害 More Bad News About Medication Errors Dynamic Chiropractic, ?Sep 14, 2006 ?by Babcock, Stephane IOM Report: 1.5 Million Injured or Killed Annually . According to the latest estimates from the Institute of Medicine (IOM), a staggering 1.5 million Americans are the victims of medication errors every year, with approximately 400,000 of those errors considered preventable. The 2006 IOM estimates are distinctly higher than previous estimates that projected between 380,000 and 800,000 preventable adverse drug events occurring annually. 24 第三十二页，共78页。 药 物 治 疗 错 误 的 危 害 More Bad News About Medication Errors Dynamic Chiropractic, ?Sep 14, 2006 ?by Babcock, Stephane 美国医学研究院(IOM)报告: 每年致伤或致死150万人 美国每年因药物治疗错误导致伤害或死亡人数达 150万人 药物治疗错误中约40万属可预防事件 2006 IOM 估计可预防药物不良事件明显高于以往 报导的每年38万至80万ADEs 24 第三十三页，共78页。 药物治疗错误的危害 24 More Bad News About Medication Errors Dynamic Chiropractic, ?Sep 14, 2006 ? by Babcock, Stephane The frequency of medication errors and preventable medication related injuries represents a very serious cause for concern The committee estimates that on average, a hospital patient is subject to at least one medication error per day ... at least one qu